Details:

Alternative Title:
Health Qual Life Outcomes
Personal Author:
Jones, James F ; Nisenbaum, Rosane ; Reeves, William C
Jones, James F ; Nisenbaum, Rosane ; Reeves, William C Less -
Description:
Background

Chronic fatigue syndrome (CFS) is characterized by profound fatigue, which substantially interferes with daily activities, and a characteristic symptom complex. Patients use a variety of prescribed and self-administered medications, vitamins, and supplements for relief of their symptoms. The objective of this study was to describe utilization of medications and supplements by persons with CFS and non-fatigued individuals representative of the general population of Wichita, Kansas.

Methods

We used a random-digit dialing telephone survey to identify persons with CFS in the general population of Wichita, Kansas. Subjects who on the basis of telephone interview met the CFS case definition, and randomly selected non-fatigued controls, were invited for a clinic evaluation that included self-reported use of medications and supplements. Sex-adjusted odds ratios and 95% confidence interval were estimated to measure the association between CFS and use of various drug categories.

Results

We clinically evaluated and classified 90 subjects as CFS during the study and also collected clinical data on 63 who never described fatigue. Subjects with CFS reported using 316 different drugs compared to 157 reported by non-fatigued controls. CFS subjects were more likely to use any drug category than controls (p = 0.0009). Pain relievers and vitamins/supplements were the two most common agents listed by both groups. In addition CFS persons were more likely to use pain relievers, hormones, antidepressants, benzodiazepines, gastro-intestinal, and central nervous system medications (Sex-adjusted odds ratios range = 2.97 – 12.78).

Conclusion

Although the reasons for increased use of these agents were not elucidated, the data indicated the CFS patients' need for symptom relief.


Subjects:
[+]
Adult Dietary Supplements Drug Therapy Fatigue Syndrome, Chronic Female Humans Kansas Male Questionnaires Research Socioeconomic Factors Telephone
Source:
Health Qual Life Outcomes. 2003; 1:74.
Document Type:
Journal Article
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:75b6d0d7ab092339aeb194633f8e0a9a3d4d6630fec9e15ce44cff485b858bb3
Download URL:
https://stacks.cdc.gov/view/cdc/3564/cdc_3564_DS1.pdf
File Type:

Supporting Files

• 	1477-7525-1-74.nxml	txt
  	license.txt	txt

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