Details:

Alternative Title:
Pediatr Infect Dis J
Publisher's site:
http://dx.doi.org/10.1097/INF.0000000000000414
Personal Author:
Person, Marissa K. ; Esposito, Douglas H. ; Holman, Robert C. ; Mehal, Jason M. ; Stoll, Barbara J.
Person, Marissa K. ; Esposito, Douglas H. ; Holman, Robert C. ; Mehal, Jason M. ; Stoll, Barbara J. Less -
Description:
Background

Infectious diseases (IDs) are an important cause of infant mortality in the United States. This study describes maternal and infant characteristics associated with infant ID deaths in the United States.

Methods

Infant deaths with an ID underlying cause of death occurring in the United States were examined using the 2008–2009 Period Linked Birth/Infant Death public use data files. Average annual ID infant mortality rates (IMRs) for singleton infants were calculated. A retrospective case-control study was conducted to determine infant and maternal risk factors for infant ID death among low (LBW) and normal (NBW) birth weight groups. Controls were defined as infants surviving to the end of their birth year. Risk factors for infant ID deaths were determined through multivariable logistic regression.

Results

An estimated 3,843 infant ID deaths occurred in the United Sates during 2008–2009, an overall ID IMR of 47.5 deaths per 100,000 live births. The mortality rates for LBW and NBW infants were 514.8 and 15.5, respectively. Male sex, younger maternal age (<25 years), a live birth order of fourth or more, and low 5-minute Apgar score were associated with increased ID death among LBW and NBW infants. Additionally, black maternal race was associated with increased ID death among LBW infants, and having an unmarried mother was associated with increased ID death among NBW infants.

Conclusions

Awareness of associations with infant ID death should help in development of further strategic measures to reduce infant ID morbidity and mortality.


Subject:
[+]
African Americans
Apgar Score
Bacteremia
Birth Order
Case-Control Studies
Cause Of Death
Communicable Diseases
Female
Hispanic Americans
Humans
Infant, Low Birth Weight
Infant, Newborn
Male
Marital Status
Maternal Age
Retrospective Studies
Risk Factors
Sex Factors
Whites

Source:
Pediatr Infect Dis J. 33(11):e280-e285.
Pubmed ID:
24853540
Pubmed Central ID:
PMC4616031
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:8118f6f3aac1da6f78b527f71bc9e6b89acb60fdd629aa25332de2be9cc45b9e
File Type:

Supporting Files

• 	nihms724346.nxml	txt
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  	nihms724346f1.jpg	jpeg

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