Varicella Zoster Virus in American Samoa: Seroprevalence and Predictive Value of Varicella Disease History Among Elementary and College Students

Mahamud, A.; Leung, J.; Masunu-Faleafaga, Y.; Teshale, E.; Williams, R.; Dulski, T.; Thieme, M.; Garcia, P.; Schmid, D.S.; Bialek, S.R.

doi:10.1017/S095026881300174X

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Varicella Zoster Virus in American Samoa: Seroprevalence and Predictive Value of Varicella Disease History Among Elementary and College Students

Published Date:

Jul 26 2013

Publisher's site:

http://dx.doi.org/10.1017/S095026881300174X New Site Icon

Source:

Epidemiol Infect. 142(5):1002-1007.

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Details:

Personal Authors:

Mahamud, A. ; Leung, J. ; Masunu-Faleafaga, Y. ; Teshale, E. ; Williams, R. ; ... More ▼

Keywords:

[+]

Pubmed ID:

23890292

Pubmed Central ID:

PMC4612350

Description:

The epidemiology of varicella is believed to differ between temperate and tropical countries. We conducted a varicella seroprevalence study in elementary and college students in the US territory of American Samoa before introduction of a routine varicella vaccination programme. Sera from 515 elementary and 208 college students were tested for the presence of varicella-zoster virus (VZV) IgG antibodies. VZV seroprevalence increased with age from 76·0% in the 4-6 years group to 97·7% in those aged ⩾23 years. Reported history of varicella disease for elementary students was significantly associated with VZV seropositivity. The positive and negative predictive values of varicella disease history were 93·4% and 36·4%, respectively, in elementary students and 97·6% and 3·0%, respectively, in college students. VZV seroprevalence in this Pacific island appears to be similar to that in temperate countries and suggests endemic VZV circulation.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

CC999999/Intramural CDC HHS/United States

Main Document Checksum:

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Supporting Files:

nihms727021.nxml

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