Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Philipp, Claire S.; Faiz, Ambarina; Heit, John A.; Kouides, Peter A.; Lukes, Andrea; Stein, Sidney F.; Byams, Vanessa; Miller, Connie H.; Kulkarni, Roshni

doi:10.1016/j.ajog.2010.10.897

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Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Published Date:

Jan 17 2011

Publisher's site:

http://dx.doi.org/10.1016/j.ajog.2010.10.897 New Site Icon

Source:

Am J Obstet Gynecol. 204(3):209.e1-209.e7.

[PDF-144.24 KB]

Details:

Personal Authors:

Philipp, Claire S. ; Faiz, Ambarina ; Heit, John A. ; Kouides, Peter A. ; Lukes, Andrea ; ... More ▼

Keywords:

[+]

Pubmed ID:

21247551

Pubmed Central ID:

PMC4598044

Description:

OBJECTIVE

The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.

STUDY DESIGN

Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.

RESULTS

Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and PBAC score of >185, respectively.

CONCLUSION

This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

CC999999/Intramural CDC HHS/United States

Supporting Files:

nihms725700.nxml

application/octet-stream

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