Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Details

• Alternative Title:
  Am J Obstet Gynecol
• Personal Author:
  Philipp, Claire S. ; Faiz, Ambarina ; Heit, John A. ; Kouides, Peter A. ; Lukes, Andrea ; Stein, Sidney F. ; Byams, Vanessa ; Miller, Connie H. ; Kulkarni, Roshni
• Description:
  OBJECTIVE
  
  The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.
  
  STUDY DESIGN
  
  Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.
  
  RESULTS
  
  Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and PBAC score of >185, respectively.
  
  CONCLUSION
  
  This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.
  
  
• Subjects:
  Adolescent Adult Cohort Studies Female Hemorrhagic Disorders Humans Mass Screening Menorrhagia Middle Aged Surveys And Questionnaires Young Adult

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• Source:
  Am J Obstet Gynecol. 204(3):209.e1-209.e7.
• Pubmed ID:
  21247551
• Pubmed Central ID:
  PMC4598044
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  204
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b5fd9de324c495eb90527f505ce2cfbda2af8d95947f672929ee5f82384f0b1c
• Download URL:
  https://stacks.cdc.gov/view/cdc/34860/cdc_34860_DS1.pdf
• File Type:
  [PDF - 144.24 KB ]