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Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia
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Jan 17 2011
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Source: Am J Obstet Gynecol. 204(3):209.e1-209.e7.
[PDF-144.24 KB]
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Alternative Title:Am J Obstet Gynecol
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Description:OBJECTIVE
The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.
STUDY DESIGN
Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.
RESULTS
Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and PBAC score of >185, respectively.
CONCLUSION
This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.
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Pubmed ID:21247551
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Pubmed Central ID:PMC4598044
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Volume:204
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Issue:3
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