Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site
Published Date:Mar 2015
Source:J Autism Dev Disord. 45(3):873-880.
Autism And Developmental Disabilities Monitoring Network
Autism Spectrum Disorder
Child Development Disorders, Pervasive
Reproducibility Of Results
Sensitivity And Specificity
Pubmed Central ID:PMC4586029
Funding:1000056630/Intramural CDC HHS/United States
UR3DD000685/DD/NCBDD CDC HHS/United States
Description:An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network&apos;s (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74-0.90)], and sensitivity [0.99 (95 % CI 0.96-1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts.
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