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CDC is committed to solving nodding syndrome a mysterious illness affecting young children in Africa
  • Published Date:
    August 4, 2015
  • Language:
    English
Filetype[PDF - 61.25 KB]


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  1. Nodding Syndrome
    Personal Author:
    Dowell, Scott F.; Sejvar, James J.; Riek, Lul; Vandemaele, Katelijn A.H.; Lamunu, Margaret; Kuesel, Annette C.; Schmutzhard, Erich; Matuja, William; Bunga, Sudhir; Foltz, Jennifer; Nutman, Thomas B.; Winkler, Andrea S.; Mbonye, Anthony K.;
    Published:
    2013
    Source:
    Emerg Infect Dis. 19(9):1374-1373.
    Description:
    An epidemic illness characterized by head nodding associated with onchocerciasis has been described in eastern Africa since the early 1960s; we summarize published reports and recent studies. Onset of nodding occurs in previously healthy 5-15-year-ol...
    File Type:
    Filetype[PDF - 560.87 KB]
  2. Developmental Outcomes in Young Children Born to Mothers with West Nile Illness during Pregnancy
    Personal Author:
    Sirois, Patricia A.; Pridjian, Gabriella; McRae, Scott; Hinckley, Alison F.; Rasmussen, Sonja A.; Kissinger, Patricia; Buekens, Pierre; Hayes, Edward B.; O’Leary, Daniel R.; Swan, Kenneth F.; Xiong, Xu; Wesson, Dawn M.;
    Published:
    Sep 05 2014
    Source:
    Birth Defects Res A Clin Mol Teratol. 100(10):792-796.
    Description:
    Background : West Nile virus (WNV) infection is associated with acute morbidity and mortality in adults and children. Information on the effects of maternal WNV illness during pregnancy on early childhood development is limited. This study was design...
    File Type:
    Filetype[PDF - 105.72 KB]
  3. Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus
    Personal Author:
    Johnson, Tory P.; Tyagi, Richa; Lee, Paul R.; Lee, Myoung-Hwa; Johnson, Kory R.; Kowalak, Jeffrey; Elkahloun, Abdel; Medynets, Marie; Hategan, Alina; Kubofcik, Joseph; Sejvar, James; Ratto, Jeffrey; Bunga, Sudhir; Makumbi, Issa; Aceng, Jane R.; Nutman, Thomas B.; Dowell, Scott F.; Nath, Avindra;
    Published:
    Feb 15 2017
    Source:
    Sci Transl Med. 9(377).
    Description:
    Nodding syndrome is an epileptic disorder of unknown etiology that occurs in children in East Africa. There is an epidemiological association with Onchocerca volvulus, the parasitic worm that causes onchocerciasis (river blindness), but there is limi...
    File Type:
    Filetype[PDF - 1.17 MB]
  4. An Epidemiologic Investigation of Potential Risk Factors for Nodding Syndrome in Kitgum District, Uganda
    Personal Author:
    Foltz, Jennifer L.; Makumbi, Issa; Sejvar, James J.; Malimbo, Mugagga; Ndyomugyenyi, Richard; Atai-Omoruto, Anne Deborah; Alexander, Lorraine N.; Abang, Betty; Melstrom, Paul; Kakooza, Angelina M.; Olara, Dennis; Downing, Robert G.; Nutman, Thomas B.; Dowell, Scott F.; Lwamafa, D. K. W.;
    Published:
    Jun 18 2013
    Source:
    PLoS One. 2013; 8(6).
    Description:
    Introduction : Nodding Syndrome (NS), an unexplained illness characterized by spells of head bobbing, has been reported in Sudan and Tanzania, perhaps as early as 1962. Hypothesized causes include sorghum consumption, measles, and onchocerciasis infe...
    File Type:
    Filetype[PDF - 331.78 KB]
  5. Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice
    Personal Author:
    Sullivan, Josefa M.; Badimon, Ana; Schaefer, Uwe; Ayata, Pinar; Gray, James; Chung, Chun-wa; von Schimmelmann, Melanie; Zhang, Fan; Garton, Neil; Smithers, Nicholas; Lewis, Huw; Tarakhovsky, Alexander; Prinjha, Rab K.; Schaefer, Anne;
    Published:
    Sep 21 2015
    Source:
    J Exp Med. 2015; 212(11):1771-1781.
    Description:
    Studies investigating the causes of autism spectrum disorder (ASD) point to genetic, as well as epigenetic, mechanisms of the disease. Identification of epigenetic processes that contribute to ASD development and progression is of major importance an...
    File Type:
    Filetype[PDF - 2.64 MB]