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Measuring lead exposure in infants, children, and other sensitive populations
  • Published Date:
Filetype[PDF-4.89 MB]

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  • Corporate Authors:
    National Research Council (U.S.), Committee on Measuring Lead in Critical Populations. ; United States, Agency for Toxic Substances and Disease Registry. ;
  • Description:
    Perspective on issues -- Historical background -- Scope and organization of the committee report -- Adverse health effects of exposure to lead -- Clinical intoxication in children -- Intoxication in adults -- Reproductive and developmental effects -- Cardiovascular effects -- Mechanisms of toxicity -- Lead exposure of sensitive populations -- Historical overview of amthropogenic lead contamination -- Source-specific lead exposure of sensitive populations -- Biologic markers of lead toxicity -- Biologic markers of exposure -- Biologic markers of effect -- Biologic markers of susceptibility -- Methods for assessing exposure to lead -- Sampling and sample handling -- Measurement of lead in specific tissues -- Mass spectrometry -- Atomic-absorption spectrometry -- Anodic-stripping voltammetry and other electrochemical methods -- Nuclear magnetic resonance spectroscopy -- Calcium-disodium EDTA provocation test -- X-ray fluorescence measurement -- Quality assurance and quality control -- Sources of lead exposure -- Adverse health effects of lead -- Markers of lead exposure and effect.

    Project was supported by the Comprehensive Environmental Response, Compensation and Liability Trust Fund through cooperative agreement with the Agency for Toxic Substances and Disease Registry, U.S. Public Health Service, Department of Health and Human Services.

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