Details:

Alternative Title:
J Am Mosq Control Assoc
Publisher's site:
http://dx.doi.org/10.2987/12-6280R.1
Personal Author:
SCOTT, MARIAH L. ; McALLISTER, JANET C.
SCOTT, MARIAH L. ; McALLISTER, JANET C. Less -
Description:
Insecticide resistance to organophosphates and carbamates can be the result of changes in acetylcholinesterase activity conferred by the ACE-1 mutation. Detection of this altered target site mutation is important in guiding informed decisions for resistance management. In this study we compared a competitive enzyme assay with a polymerase chain reaction assay utilizing a restriction enzyme. Both assays detected the ACE-1 mutation in Culex quinquefasciatus and agreement was 100%. The costs and benefits of each assay are presented.
Subject:
[+]
ACE-1 Mutation
Acetylcholinesterase
Animals
Article
Cholinesterase Inhibitors
Culex
Culex Quinquefasciatus
Gene Expression Regulation, Enzymologic
Insecticide Resistance
Insecticides
Organophosphate Resistance
Acetylcholinesterase

Source:
J Am Mosq Control Assoc. 28(4):323-326.
Pubmed ID:
23393758
Pubmed Central ID:
PMC4562403
Document Type:
Journal Article
Funding:
JVM6/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f1e64f010c50d1fa5f28a177bdd247f83f1f3213257bc52556aeebf1bb540e3b
File Type:

Supporting Files

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