Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery

Details

• Alternative Title:
  Adv Mater
• Personal Author:
  Subramaniam, Prasad ; Lee, Seung Jae ; Shah, Shreyas ; Patel, Sahishnu ; Starovoytov, Valentin ; Lee, Ki-Bum
• Description:
  The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS(2) (ZAIS) quantum dots for cellular imaging and siRNA delivery.
• Subjects:
  Article Biocompatible Materials Cell Line, Tumor Drug Carriers Fluorescent Dyes Gene Transfer Techniques Humans Microscopy, Fluorescence Nanomaterial Library Non-toxic Quantum Dots Quantum Dots RNA, Small Interfering SiRNA Delivery Sonochemistry Stem Cell Imaging Stem Cells Sulfides Zinc Compounds

  More +
• Source:
  Adv Mater. 24(29):4014-4019
• Pubmed ID:
  22744954
• Pubmed Central ID:
  PMC3668976
• Document Type:
  Journal Article
• Funding:
  DP2 OD006462/OD/NIH HHS/United States ; 1DP20D006462-01/DP/NCCDPHP CDC HHS/United States
• Volume:
  24
• Issue:
  29
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:962a9f31a89ca5e8f2250954b206bfacc707045ec4b1bba51880a1d628c63c88
• Download URL:
  https://stacks.cdc.gov/view/cdc/33573/cdc_33573_DS1.pdf
• File Type:
  [PDF - 1.99 MB ]