Welcome to CDC Stacks | FcγRI (CD64): an identity card for intestinal macrophages - 33551 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
FcγRI (CD64): an identity card for intestinal macrophages
Filetype[PDF - 695.72 KB]


Details:
  • Personal Authors:
  • Keywords:
  • Pubmed ID:
    23255010
  • Pubmed Central ID:
    PMC3644030
  • Description:
    Macrophages are becoming increasingly recognized as key cellular players in intestinal immune homeostasis. However, differentiating between macrophages and dendritic cells (DCs) is often difficult, and finding a specific phenotypic signature for intestinal macrophage identification has remained elusive. In this issue of the European Journal of Immunology, Tamoutounour et al. [Eur. J. Immunol. 2012. 42: 3150-3166] identify CD64 as a specific macrophage marker that can be used to discriminate DCs from macrophages in the murine small and large intestine, under both steady-state and inflammatory conditions. The authors also propose a sequential 'monocyte-waterfall' model for intestinal macrophage differentiation, with implications for immune tolerance and inflammation at the gut mucosal interface. This Commentary will discuss the advantages and potential limitations of CD64 as a marker for intestinal macrophages.

  • Document Type:
    Journal Article
  • Collection(s):
    CDC Public Access
  • Funding:
    DP2 2009A054301/DP/NCCDPHP CDC HHS/United States
    DP2 OD006512/OD/NIH HHS/United States
    P30 AI060354/AI/NIAID NIH HHS/United States
No Related Documents.
You May Also Like:
  1. AN INTESTINAL THREADWORM AS A RESERVOIR AND INTERMEDIATE HOST FOR SWINE INFLUENZA VIRUS
    Personal Author:
    Shotts, Emmett B.; Foster, John W.; Brugh, Max; Jordan, Helen E.; McQueen, James L.;
    Published:
    Jan 31 1968
    Source:
    J Exp Med. 127(2):359-369.
    Description:
    A laboratory model exemplifying Shope's concept of virus carriage by helminths was developed using Strongyloides ratti (Sandground, 1925), swine influenza virus, and caesarean-originated, barrier-sustained (COBS) mice and rats. It was shown that S. r...
    File Type:
    Filetype[PDF - 579.89 KB]
  2. An Interferon-Related Signature in the Transcriptional Core Response of Human Macrophages to Mycobacterium tuberculosis Infection
    Personal Author:
    Wu, Kang; Dong, Dandan; Fang, Hai; Levillain, Florence; Jin, Wen; Mei, Jian; Gicquel, Brigitte; Du, Yanzhi; Wang, Kankan; Gao, Qian; Neyrolles, Olivier; Zhang, Ji;
    Published:
    Jun 04 2012
    Source:
    PLoS One. 2012; 7(6).
    Description:
    The W-Beijing family of Mycobacterium tuberculosis (Mtb) strains is known for its high-prevalence and -virulence, as well as for its genetic diversity, as recently reported by our laboratories and others. However, little is known about how the immune...
    File Type:
    Filetype[PDF - 2.87 MB]
  3. Intestinal parasite guidelines for domestic medical examination for newly arrived refugees
    Corporate Author:
    National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Global Migration and Quarantine.
    Published:
    November 6, 2013
    Description:
    It is estimated that more than one billion people are infected with soil-transmitted helminths (STH), 200 million with Schistosoma spp., and 100 million with Strongyloides. These parasites are some of the most common infections in refugees. Although ...
    File Type:
    Filetype[PDF - 589.13 KB]
  4. Risk Factors for Intestinal Invasive Amebiasis in Japan, 2003–2009
    Personal Author:
    Nagata, Naoyoshi; Shimbo, Takuro; Akiyama, Junichi; Nakashima, Ryo; Nishimura, So; Yada, Tomoyuki; Watanabe, Koji; Oka, Shinichi; Uemura, Naomi;
    Published:
    May 2012
    Source:
    Emerg Infect Dis. 18(5):717-724.
    Description:
    We determined yearly change in prevalence and risk factors for amebic colitis caused by intestinal invasive amebiasis among persons who underwent endoscopy and assessed differences between HIV-positive and HIV-negative persons in Japan. A total of 10...
    File Type:
    Filetype[PDF - 561.93 KB]
  5. CDC CARE card
    Corporate Author:
    Centers for Disease Control and Prevention (U.S.)
    Published:
    March 31, 2015
    Series:
    Ebola CARE kit
    Description:
    Part of the CDC Check and Report Ebola (CARE) kit issued to travelers to help them look for Ebola symptoms to communicate with health departments each day for 21 days after departure from a country that has an Ebola outbreak. : CS254910-C : care-card...
    File Type:
    Filetype[PDF - 97.35 KB]