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Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels
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  1. Investigation of human exposure to triclocarban after showering, and preliminary evaluation of its biological effects
    Personal Author:
    Schebb, Nils Helge; Inceoglu, Bora; Ahn, Ki Chang; Morisseau, Christophe; Gee, Shirley; Hammock, Bruce D.;
    Published:
    Mar 07 2011
    Source:
    Environ Sci Technol. 45(7):3109-3115.
    Description:
    The antibacterial soap additive triclocarban (TCC) is widely used in personal care products. TCC has a high environmental persistence. We developed and validated a sensitive online solid-phase extraction-LC-MS/MS method to rapidly analyze TCC and its...
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  2. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay
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    Ahn, Ki Chang; Ranganathan, Anupama; Bever, Candace S.; Hwang, Sung Hee; Holland, Erika B.; Morisseau, Kevin; Pessah, Isaac N.; Hammock, Bruce D.; Gee, Shirley J.;
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    Environ Sci Technol. 50(7):3754-3761.
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    A sensitive, competitive enzyme-linked immunosorbent assay (ELISA) for the detection of the antimicrobial triclosan (TCS; 2,4,4'-trichloro-2'-hydroxydiphenyl ether) was developed. Novel immunizing haptens were synthesized by derivatizing at...
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  3. Methods for the determination of biomarkers of exposure to emerging pollutants in human specimens
    Personal Author:
    Yusa, Vicent; Ye, Xiaoyun; Calafat, Antonia M.;
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    Sep 2012
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    Trends Analyt Chem. 38:129-142.
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    Biomonitoring is a very useful tool for assessing human exposure to environmental pollutants. This review discusses recent methods for the quantitative measurement of biomarkers of exposure to different classes of chemicals used in personal-care prod...
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  4. Bioconcentration, Metabolism and Excretion of Triclocarban in larval Qurt Medaka (Oryzias latipes)
    Personal Author:
    Schebb, Nils Helge; Flores, Ida; Kurobe, Tomofumi; Franze, Bastian; Ranganathan, Anupama; Hammock, Bruce D.; Teh, Swee;
    Published:
    Aug 04 2011
    Source:
    Aquat Toxicol. 105(3-4):448-454.
    Description:
    The antimicrobial triclocarban (TCC) is frequently found in personal care products and commonly observed in surface waters and sediments. Due to its long environmental persistence TCC accumulates in sewage sludge. It also shows a high unintended biol...
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  5. Biomarkers of Exposure to Triclocarban in Urine and Serum
    Personal Author:
    Ye, Xiaoyun; Zhou, Xiaoliu; Furr, Johnathan; Ahn, Ki Chang; Hammock, Bruce D.; Gray, Earl L.; Calafat, Antonia M.;
    Published:
    May 23 2011
    Source:
    Toxicology. 286(1-3):69-74.
    Description:
    3,4,4'-Trichlorocarbanilide (triclocarban, TCC) is widely used as an antimicrobial agent in a variety of consumer and personal care products. TCC is considered a potential endocrine disruptor, but its potential toxic effects in humans are still large...
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