Social networks and HCV viremia among anti-HCV positive rural drug users

YOUNG, A. M.; JONAS, A. B.; HAVENS, J. R.

doi:10.1017/S0950268812000696

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Social networks and HCV viremia among anti-HCV positive rural drug users

Published Date:

Apr 19 2012

Publisher's site:

http://dx.doi.org/10.1017/S0950268812000696

Source:

Epidemiol Infect. 141(2):402-411.

Language:

English

[PDF-304.97 KB]

Details:

Alternative Title:

Epidemiol Infect

Personal Author:

YOUNG, A. M. ; JONAS, A. B. ; HAVENS, J. R. ;

Description:

Although social networks are known to play an important role in drug-using behaviours associated with hepatitis C virus (HCV) infection, literature on social networks and HCV is inconsistent. This exploratory study examined HCV RNA distribution within a social network of anti-HCV-positive non-medical prescription opioid users (NMPOUs) in rural Appalachia. Participants were tested serologically for HCV RNA, and behavioural, demographic, and network data were collected using interview-administered questionnaires. Multivariate analyses were performed using logistic regression. Behavioural and demographic characteristics did not differ by RNA status. In the multivariate model, recent injecting drug users (IDUs) were more likely to be RNA positive [odds ratio (OR) 4·06, 95% confidence interval (CI) 1·04-15·83], and turnover into an IDU's drug network was significantly protective (OR 0·15, 95% CI 0·03-0·75). This is the first study to date to examine HCV distribution in rural NMPOUs from a network perspective and demonstrates that network characteristics significantly contribute to the epidemiology of HCV in this understudied, high-risk population.

Subject:

[+]

Pubmed ID:

22717190

Pubmed Central ID:

PMC3469752

Document Type:

Journal Article

Funding:

R01 DA024598/DA/NIDA NIH HHS/United States ; R01-DA02498/DA/NIDA NIH HHS/United States ; U48DP001932/DP/NCCDPHP CDC HHS/United States ;

Place as Subject:

Kentucky

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

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