Details:

Alternative Title:
Epidemiol Infect
Publisher's site:
http://dx.doi.org/10.1017/S0950268812000696
Personal Author:
YOUNG, A. M. ; JONAS, A. B. ; HAVENS, J. R.
YOUNG, A. M. ; JONAS, A. B. ; HAVENS, J. R. Less -
Description:
Although social networks are known to play an important role in drug-using behaviours associated with hepatitis C virus (HCV) infection, literature on social networks and HCV is inconsistent. This exploratory study examined HCV RNA distribution within a social network of anti-HCV-positive non-medical prescription opioid users (NMPOUs) in rural Appalachia. Participants were tested serologically for HCV RNA, and behavioural, demographic, and network data were collected using interview-administered questionnaires. Multivariate analyses were performed using logistic regression. Behavioural and demographic characteristics did not differ by RNA status. In the multivariate model, recent injecting drug users (IDUs) were more likely to be RNA positive [odds ratio (OR) 4·06, 95% confidence interval (CI) 1·04-15·83], and turnover into an IDU's drug network was significantly protective (OR 0·15, 95% CI 0·03-0·75). This is the first study to date to examine HCV distribution in rural NMPOUs from a network perspective and demonstrates that network characteristics significantly contribute to the epidemiology of HCV in this understudied, high-risk population.
Subject:
[+]
Adult Analgesics, Opioid Article Cohort Studies Drug Users Female Hepacivirus Hepatitis C Hepatitis C Antibodies Humans Injections, Intravenous Logistic Models Longitudinal Studies Male Prescription Drug Misuse RNA, Viral Rural Population Social Support Viremia
Source:
Epidemiol Infect. 141(2):402-411.
Pubmed ID:
22717190
Pubmed Central ID:
PMC3469752
Document Type:
Journal Article
Funding:
R01 DA024598/DA/NIDA NIH HHS/United States ; R01-DA02498/DA/NIDA NIH HHS/United States ; U48DP001932/DP/NCCDPHP CDC HHS/United States
R01 DA024598/DA/NIDA NIH HHS/United States ; R01-DA02498/DA/NIDA NIH HHS/United States ; U48DP001932/DP/NCCDPHP CDC HHS/United States Less -
Place as Subject:
Kentucky
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:85920cfee8f41fe593c0d5d443befc40a777abeb1db7deb0c9d59596f0183173
Download URL:
https://stacks.cdc.gov/view/cdc/33446/cdc_33446_DS1.pdf
File Type:

Supporting Files

• 	nihms372139.nxml	bin
  	nihms372139f1.gif	gif
  	nihms372139f1.jpg	jpeg

More +