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Therapeutic Monitoring of Voriconazole in Children Less Than 3 Years of Age: A Case Report and Summary of Voriconazole Concentrations for 10 Children
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6 2012
Source: Pediatr Infect Dis J. 31(6):632-635 -
Alternative Title:Pediatr Infect Dis J
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Description:Voriconazole is the treatment of choice for invasive aspergillosis and its use is increasing in pediatrics. Minimal pharmacokinetic data exist in young children. We report voriconazole concentrations for 10 children <3 years of age and pharmacokinetic parameters for 1 infant who had therapeutic drug monitoring performed. Trough concentrations were unpredictable based on dose, highlighting the need to follow values during therapy.
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Pubmed ID:22301479
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Pubmed Central ID:PMC3356483
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