Details:

Alternative Title:
Contemp Clin Trials
Personal Author:
Chavula, Charity; Long, Dustin; Mzembe, Enalla; Kayira, Dumbani; Chasela, Charles; ... More +
Chavula, Charity; Long, Dustin; Mzembe, Enalla; Kayira, Dumbani; Chasela, Charles; Hudgens, Michael G.; Hosseinipour, Mina; King, Caroline C.; Ellington, Sascha; Chigwenembe, Margret; Jamieson, Denise J.; van der Horst, Charles; Less -
Corporate Authors:
for the BAN Study Team;
Description:
The Data and Safety Monitoring Board (DSMB) for the Breastfeeding, Antiretrovirals, and Nutrition study, a clinical trial aimed to prevent postnatal HIV transmission, recommended halting randomization to the enhanced standard-of-care (control) arm. The 67 mother-infant pairs on the control arm and less than 21 weeks postpartum at the time of the DSMB recommendation were read a script informing them of the DSMB decision and offering them the maternal or infant antiretroviral interventions for the remainder of the 28-week breastfeeding period. This paper describes the BAN study response to the DSMB decision and what the women on the control arm chose, when given a choice to start the maternal or infant antiretroviral interventions.
Subject:
[+]
Adult
Anti-HIV Agents
Antiretorival Prophylaxis
Article
Breastfeeding
Breast Feeding
Female
Follow-Up Studies
HIV-1
HIV Infections
Humans
Infant
Infant, Newborn
Infectious Disease Transmission, Vertical
Milk, Human
Postnatal HIV Transmission
Prognosis
Retrospective Studies
Young Adult

Source:
Contemp Clin Trials. 33(1):55-59;
Pubmed ID:
22041453
Pubmed Central ID:
PMC3253884
Document Type:
Journal Article;
Funding:
SIP 22-09 U48-DP001944-01/DP/NCCDPHP CDC HHS/United States; U48DP001944/ACL HHS/United States; R24 TW00798/TW/FIC NIH HHS/United States; SIP 13-01 U48-CCU409660-09/PHS HHS/United States; SIP 26-04 U48-DP000059-01/DP/NCCDPHP CDC HHS/United States; ... More +
SIP 22-09 U48-DP001944-01/DP/NCCDPHP CDC HHS/United States; U48DP001944/ACL HHS/United States; R24 TW00798/TW/FIC NIH HHS/United States; SIP 13-01 U48-CCU409660-09/PHS HHS/United States; SIP 26-04 U48-DP000059-01/DP/NCCDPHP CDC HHS/United States; P30 AI050410-15/AI/NIAID NIH HHS/United States; P30-AI50410/AI/NIAID NIH HHS/United States; U48 DP000059/DP/NCCDPHP CDC HHS/United States; 2-D43 TW01039-06/TW/FIC NIH HHS/United States; P30 AI050410/AI/NIAID NIH HHS/United States; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:2c553399b8b3cc0d41c18763ea04adcc840b94e94ed411054e4cb03d29df3a46
File Type:

Supporting Files

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