Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review

Yokell, Michael A.; Zaller, Nickolas D.; Green, Traci C.; Rich, Josiah D.

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Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review

Published Date:

Mar 2011

Source:

Curr Drug Abuse Rev. 2011; 4(1):28-41

Language:

English

[PDF-90.25 KB]

Details:

Alternative Title:

Curr Drug Abuse Rev

Personal Author:

Yokell, Michael A. ; Zaller, Nickolas D. ; Green, Traci C. ; Rich, Josiah D. ;

Description:

The diversion, misuse, and non-medically supervised use of buprenorphine and buprenorphine/naloxone by opioid users are reviewed. Buprenorphine and buprenorphine/naloxone are used globally as opioid analgesics and in the treatment of opioid dependency. Diversion of buprenorphine and buprenorphine/naloxone represents a complex medical and social issue, and has been widely documented in various geographical regions throughout the world. We first discuss the clinical properties of buprenorphine and its abuse potential. Second, we discuss its diversion and illicit use on an international level, as well as motivations for those activities. Third, we examine the medical risks and benefits of buprenorphine's non-medically supervised use and misuse. These risks and benefits include the effect of buprenorphine's use on HIV risk and the risk of its concomitant use with other medications and drugs of abuse. Finally, we discuss the implications of diversion, misuse, and non-medically supervised use (including potential measures to address issues of diversion); and potential areas for further research.

Subject:

[+]

Pubmed ID:

21466501

Pubmed Central ID:

PMC3154701

Document Type:

Journal Article

Funding:

P30 DA013868/DA/NIDA NIH HHS/United States ; R21 CE001846/CE/NCIPC CDC HHS/United States ; K24 DA022112/DA/NIDA NIH HHS/United States ; P30DA013868/DA/NIDA NIH HHS/United States ; K24 DA022112-01A2/DA/NIDA NIH HHS/United States ; ... More ▼

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

File Type:

Supporting Files:

nihms314965.nxml

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Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review

Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review

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