Welcome to CDC stacks |
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Seasonal variation in host susceptibility and cycles of certain infectious diseases.
  • Published Date:
    2001 May-Jun
  • Source:
    Emerg Infect Dis. 7(3):369-374.
Filetype[PDF-69.46 KB]


Details:
  • Alternative Title:
    Emerg Infect Dis
  • Personal Author:
    Dowell, S. F.
  • Description:
    Seasonal cycles of infectious diseases have been variously attributed to changes in atmospheric conditions, the prevalence or virulence of the pathogen, or the behavior of the host. Some observations about seasonality are difficult to reconcile with these explanations. These include the simultaneous appearance of outbreaks across widespread geographic regions of the same latitude; the detection of pathogens in the off-season without epidemic spread; and the consistency of seasonal changes, despite wide variations in weather and human behavior. In contrast, an increase in susceptibility of the host population, perhaps linked to the annual light/dark cycle and mediated by the pattern of melatonin secretion, might account for many heretofore unexplained features of infectious disease seasonality. Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans. If such physiologic changes underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable.

  • Subject:
  • Document Type:
    Journal Article
  • Collection(s):
    Emerging Infectious Diseases
    CDC Public Access
  • Main Document Checksum:
No Related Documents.
You May Also Like:
  1. Seasonal Patterns of Invasive Pneumococcal Disease
    Personal Author:
    Dowell, Scott F.; Whitney, Cynthia G.; Wright, Carolyn; Rose, Charles E.; Schuchat, Anne;
    Published Date:
    May 2003
    Source:
    Emerg Infect Dis. 9(5):574-579.
    Description:
    Pneumococcal infections increase each winter, a phenomenon that has not been well explained. We conducted population-based active surveillance for all cases of invasive pneumococcal disease in seven states; plotted annualized weekly rates by geograph...
    File Type:
    Filetype[PDF - 738.58 KB]
  2. Seasonal Patterns of Invasive Pneumococcal Disease
    Personal Author:
    Dowell, Scott F.; Whitney, Cynthia G.; Wright, Carolyn; Rose, Charles E.; Schuchat, Anne;
    Published Date:
    Jul 2004
    Source:
    Emerg Infect Dis. 9(5):574-579.
    Description:
    The purpose of these experiments was to test the equivalence of pulmonary artery, urinary bladder, tympanic, rectal and femoral artery methods of temperature measurement in healthy and critically ill swine under clinical intensive care unit (ICU) con...
    File Type:
    Filetype[PDF - 738.58 KB]
  3. Climate variability and change in the United States: potential impacts on vector- and rodent-borne diseases.
    Personal Author:
    Gubler, Duane J.; Reiter, Paul.; Ebi, Kristi L.; Yap, Wendy.; Nasci, Roger.; Patz, Jonathan A.;
    Published Date:
    May 2001
    Source:
    Environ Health Perspect. 109(Suppl 2):223-233.
    Description:
    Diseases such as plague, typhus, malaria, yellow fever, and dengue fever, transmitted between humans by blood-feeding arthropods, were once common in the United States. Many of these diseases are no longer present, mainly because of changes in land u...
    File Type:
    Filetype[PDF - 483.84 KB]
  4. Competence of American robins as reservoir hosts for Lyme disease spirochetes.
    Personal Author:
    Richter, D.; Spielman, A.; Komar, N.; Matuschka, F. R.;
    Published Date:
    2000 Mar-Apr
    Source:
    Emerg Infect Dis. 6(2):133-138.
    Description:
    To explore the competence of American robins as a reservoir for Lyme disease spirochetes, we determined the susceptibility of these birds to tickborne spirochetes and their subsequent infectivity for larval vector ticks. Robins acquired infection and...
    File Type:
    Filetype[PDF - 243.55 KB]
  5. Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature
    Personal Author:
    Lowen, Anice C; Mubareka, Samira; Steel, John; Palese, Peter;
    Published Date:
    Oct 19 2007
    Source:
    PLoS Pathog. 2007; 3(10).
    Description:
    In temperate regions influenza epidemics recur with marked seasonality: in the northern hemisphere the influenza season spans November to March, while in the southern hemisphere epidemics last from May until September. Although seasonality is one of ...
    File Type:
    Filetype[PDF - 862.13 KB]