Obese women less likely to have low serum ferritin, Nicaragua

Details

• Alternative Title:
  Public Health Nutr
• Personal Author:
  Wendt, Amanda S ; Jefferds, Maria E ; Perrine, Cria G ; Halleslevens, Patricia ; Sullivan, Kevin M
• Description:
  Objective
  
  To examine the association between overweight and obesity and serum ferritin among women of reproductive age (15–49 years) in Nicaragua, considering the effect of α1-acid glycoprotein (AGP), a marker of inflammation.
  
  Design
  
  We analysed data from the 2004–05 Nicaraguan Integrated Surveillance System for Nutrition Interventions. Three logistic regression models were analysed with low serum ferritin (<15 μg/l) as the dependent variable: (i) overweight or obese status and covariates; (ii) model 1 plus AGP; and (iii) model 1 restricted to only women with normal AGP levels (≤1·0 g/l).
  
  Setting
  
  Nicaragua.
  
  Subjects
  
  Included in this analysis were 832 non-pregnant mother/caregivers (15–49 years) surveyed in 2004–2005.
  
  Results
  
  In the sample, prevalence of overweight and obesity was 31·8 % and 19·2 %, respectively, and 27·6 % had low serum ferritin. In model 1, the adjusted OR of low serum ferritin was 0·74 (95 % CI 0·52, 1·05) for overweight women and 0·42 (95 % CI 0·26, 0·65) for obese women. In model 2, AGP was significantly independently associated with low serum ferritin (adjusted OR=0·56, 95 % CI 0·34, 0·92) while the adjusted OR for overweight and obesity were largely unchanged. Excluding women with elevated AGP did not appreciably affect the relationship between overweight or obesity and low serum ferritin (model 3).
  
  Conclusions
  
  Overall, in this population of reproductive-age women, obese women were less likely to have low serum ferritin levels, and this was independent of inflammation as measured by AGP.
  
  
• Subjects:
  Adolescent Adult Biomarkers Female Ferritins Humans Logistic Models Middle Aged Obesity Orosomucoid Overweight Population Surveillance Young Adult

  More +
• Source:
  Public Health Nutr. 18(4):736-741
• Pubmed ID:
  24848519
• Pubmed Central ID:
  PMC4547454
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States ; T32 HD052460/HD/NICHD NIH HHS/United States ; 2T32HD052460/HD/NICHD NIH HHS/United States
• Place as Subject:
  Nicaragua
• Volume:
  18
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:96b738b09aba6f42170a62f5707b07b45348669e3c61eb411a5d7fa387f875ed
• Download URL:
  https://stacks.cdc.gov/view/cdc/33032/cdc_33032_DS1.pdf
• File Type:
  [PDF - 192.89 KB ]