Details:

Alternative Title:
Public Health Nutr
Personal Author:
Wendt, Amanda S ; Jefferds, Maria E ; Perrine, Cria G ; Halleslevens, Patricia ; Sullivan, Kevin M ;
Wendt, Amanda S ; Jefferds, Maria E ; Perrine, Cria G ; Halleslevens, Patricia ; Sullivan, Kevin M ; Less -
Description:
Objective To examine the association between overweight and obesity and serum ferritin among women of reproductive age (15–49 years) in Nicaragua, considering the effect of α1-acid glycoprotein (AGP), a marker of inflammation. Design We analysed data from the 2004–05 Nicaraguan Integrated Surveillance System for Nutrition Interventions. Three logistic regression models were analysed with low serum ferritin (<15 μg/l) as the dependent variable: (i) overweight or obese status and covariates; (ii) model 1 plus AGP; and (iii) model 1 restricted to only women with normal AGP levels (≤1·0 g/l). Setting Nicaragua. Subjects Included in this analysis were 832 non-pregnant mother/caregivers (15–49 years) surveyed in 2004–2005. Results In the sample, prevalence of overweight and obesity was 31·8 % and 19·2 %, respectively, and 27·6 % had low serum ferritin. In model 1, the adjusted OR of low serum ferritin was 0·74 (95 % CI 0·52, 1·05) for overweight women and 0·42 (95 % CI 0·26, 0·65) for obese women. In model 2, AGP was significantly independently associated with low serum ferritin (adjusted OR=0·56, 95 % CI 0·34, 0·92) while the adjusted OR for overweight and obesity were largely unchanged. Excluding women with elevated AGP did not appreciably affect the relationship between overweight or obesity and low serum ferritin (model 3). Conclusions Overall, in this population of reproductive-age women, obese women were less likely to have low serum ferritin levels, and this was independent of inflammation as measured by AGP.
Subject:
[+]
Adolescent
Adult
Biomarkers
Female
Ferritins
Humans
Logistic Models
Middle Aged
Obesity
Orosomucoid
Overweight
Population Surveillance
Young Adult

Source:
Public Health Nutr. 18(4):736-741
Pubmed ID:
24848519
Pubmed Central ID:
PMC4547454
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ; T32 HD052460/HD/NICHD NIH HHS/United States ; 2T32HD052460/HD/NICHD NIH HHS/United States ;
CC999999/Intramural CDC HHS/United States ; T32 HD052460/HD/NICHD NIH HHS/United States ; 2T32HD052460/HD/NICHD NIH HHS/United States ; Less -
Place as Subject:
Nicaragua ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:96b738b09aba6f42170a62f5707b07b45348669e3c61eb411a5d7fa387f875ed
File Type:

Supporting Files

• nihms716404.nxml

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