Phylogeography of Influenza A(H3N2) Virus in Peru, 2010–2012

Pollett, Simon; Nelson, Martha I.; Kasper, Matthew; Tinoco, Yeny; Simons, Mark; Romero, Candice; Silva, Marita; Lin, Xudong; Halpin, Rebecca A.; Fedorova, Nadia; Stockwell, Timothy B.; Wentworth, David; Holmes, Edward C.; Bausch, Daniel G.

doi:10.3201/eid2108.150084

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Phylogeography of Influenza A(H3N2) Virus in Peru, 2010–2012

Published Date:

Aug 2015

Publisher's site:

http://dx.doi.org/10.3201/eid2108.150084 New Site Icon

Source:

Emerg Infect Dis. 21(8):1330-1338.

[PDF-2.76 MB]

Details:

Personal Authors:

Pollett, Simon ; Nelson, Martha I. ; Kasper, Matthew ; Tinoco, Yeny ; Simons, Mark ; ... More ▼

Keywords:

[+]

Pubmed ID:

26196599

Pubmed Central ID:

PMC4517729

Description:

It remains unclear whether lineages of influenza A(H3N2) virus can persist in the tropics and seed temperate areas. We used viral gene sequence data sampled from Peru to test this source-sink model for a Latin American country. Viruses were obtained during 2010-2012 from influenza surveillance cohorts in Cusco, Tumbes, Puerto Maldonado, and Lima. Specimens positive for influenza A(H3N2) virus were randomly selected and underwent hemagglutinin sequencing and phylogeographic analyses. Analysis of 389 hemagglutinin sequences from Peru and 2,192 global sequences demonstrated interseasonal extinction of Peruvian lineages. Extensive mixing occurred with global clades, but some spatial structure was observed at all sites; this structure was weakest in Lima and Puerto Maldonado, indicating that these locations may experience greater viral traffic. The broad diversity and co-circulation of many simultaneous lineages of H3N2 virus in Peru suggests that this country should not be overlooked as a potential source for novel pandemic strains.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	license.txt	text/plain
	15-0084-F1.gif	image/gif
	15-0084-F1.jpg	image/jpeg
	15-0084-F2.gif	image/gif
	15-0084-F2.jpg	image/jpeg
	15-0084-F3.gif	image/gif
	15-0084-F3.jpg	image/jpeg
	15-0084-Techapp-s1.pdf	application/pdf
	15-0084.nxml	text/plain

No Related Documents.

You May Also Like:

Global circulation patterns of seasonal influenza viruses vary with antigenic drift

Personal Author:

Bedford, Trevor; Riley, Steven; Barr, Ian G.; Broor, Shobha; Chadha, Mandeep; Cox, Nancy J.; Daniels, Rodney S.; Gunasekaran, C. Palani; Hurt, Aeron C.; Kelso, Anne; Klimov, Alexander; Lewis, Nicola S.; Li, Xiyan; McCauley, John W.; Odagiri, Takato; Potdar, Varsha; Rambaut, Andrew; Shu, Yuelong; Skepner, Eugene; Smith, Derek J.; Suchard, Marc A.; Tashiro, Masato; Wang, Dayan; Xu, Xiyan; Lemey, Philippe; Russell, Colin A.;

Published:

Jun 08 2015

Source:

Nature. 523(7559):217-220.

Description:

Understanding the spatiotemporal patterns of emergence and circulation of new human seasonal influenza virus variants is a key scientific and public health challenge. The global circulation patterns of influenza A/H3N2 viruses are well characterized,...

File Type:

[PDF - 3.02 MB]
Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico

Personal Author:

Nelson, Martha I.; Souza, Carine K.; Trovão, Nídia S.; Diaz, Andres; Mena, Ignacio; Rovira, Albert; Vincent, Amy L.; Torremorell, Montserrat; Marthaler, Douglas; Culhane, Marie R.;

Published:

April 17 2019

Source:

Emerg Infect Dis. 25(4):691-700

Description:

The genetic diversity of influenza A viruses circulating in swine in Mexico complicates control efforts in animals and presents a threat to humans, as shown by influenza A(H1N1)pdm09 virus. To describe evolution of swine influenza A viruses in Mexico...

File Type:

[PDF - 3.21 MB]
Capsular Switching and Other Large-Scale Recombination Events in Invasive Sequence Type 1 Group B Streptococcus

Personal Author:

Neemuchwala, Alefiya; Teatero, Sarah; Athey, Taryn B.T.; McGeer, Allison; Fittipaldi, Nahuel;

Published:

Nov 2016

Source:

Emerg Infect Dis. 22(11):1941-1944.

Description:

We report several cases of recombination events leading to capsular switching among sequence type (ST) 1 group B Streptococcus strains. These strains otherwise shared a common genome backbone with serotype V ST1 strains. However, the genomes of ST1 s...

File Type:

[PDF - 1.76 MB]
Incidence of Norovirus-Associated Diarrhea, Shanghai, China, 2012–2013

Personal Author:

Yu, Jianxing; Ye, Chuchu; Lai, Shengjie; Zhu, Weiping; Zhang, Zike; Geng, Qibin; Xue, Caoyi; Yang, Weizhong; Wu, Shuyu; Hall, Aron J.; Sun, Qiao; Li, Zhongjie;

Published:

Feb 2017

Source:

Emerg Infect Dis. 23(2):312-315.

Description:

We conducted sentinel-based surveillance for norovirus in the Pudong area of Shanghai, China, during 2012-2013, by analyzing 5,324 community surveys, 408,024 medical records, and 771 laboratory-confirmed norovirus infections among 3,877 diarrhea case...

File Type:

[PDF - 995.32 KB]
Migration and Persistence of Human Influenza A Viruses, Vietnam, 2001–2008

Personal Author:

Le, Mai Quynh; Lam, Ha Minh; Cuong, Vuong Duc; Lam, Tommy Tsan-Yuk; Halpin, Rebecca A.; Wentworth, David E.; Hien, Nguyen Tran; Thanh, Le Thi; Phuong, Hoang Vu Mai; Horby, Peter; Boni, Maciej F.;

Published:

Nov 2013

Source:

Emerg Infect Dis. 19(11):1756-1765.

Description:

Understanding global influenza migration and persistence is crucial for vaccine strain selection. Using 240 new human influenza A virus whole genomes collected in Vietnam during 2001-2008, we looked for persistence patterns and migratory connections ...

File Type:

[PDF - 711.84 KB]