CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Challenges in Studying Modifiable Risk Factors for Birth Defects
-
3 2015
-
-
Source: Curr Epidemiol Rep. 2(1):23-30
Details:
-
Alternative Title:Curr Epidemiol Rep
-
Personal Author:
-
Description:Conducting research to identify modifiable risk factors for birth defects is difficult for a variety of reasons. While some challenges are familiar to researchers across many disciplines, the confluence of issues affecting birth defects research may not be well understood by those outside of the field. This article describes several methodological challenges to the study of birth defects and ways these challenges might be addressed: (1) ascertainment, definition and classification of birth defects; (2) exposure assessment on modifiable risk factors; (3) analytical challenges related to small numbers and multiple statistical tests; (4) the role of genetics, including the collection of specimens and analysis of genetic data; and (5) challenges in translating research and demonstrating public health impact. Understanding these issues is important for researchers planning studies, reviewers evaluating the scientific merit of results from these studies, and consumers of the research, including fellow researchers, policy makers, health care providers, and families.
-
Keywords:
-
Source:
-
Pubmed ID:26236577
-
Pubmed Central ID:PMC4516719
-
Document Type:
-
Funding:
-
Volume:2
-
Issue:1
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: