Details:

Alternative Title:
Sci Rep
Publisher's site:
http://dx.doi.org/10.1038/srep07630
Personal Author:
Wu, Donglin ; Zou, Shumei ; Bai, Tian ; Li, Jing ; Zhao, Xiang ; ... More +
Wu, Donglin ; Zou, Shumei ; Bai, Tian ; Li, Jing ; Zhao, Xiang ; Yang, Lei ; Liu, Hongmin ; Li, Xiaodan ; Yang, Xianda ; Xin, Li ; Xu, Shuang ; Zou, Xiaohui ; Li, Xiyan ; Wang, Ao ; Guo, Junfeng ; Sun, Bingxin ; Huang, Weijuan ; Zhang, Ye ; Li, Xiang ; Gao, Rongbao ; Shen, Bo ; Chen, Tao ; Dong, Jie ; Wei, Hejiang ; Wang, Shiwen ; Li, Qun ; Li, Dexin ; Wu, Guizhen ; Feng, Zijian ; Gao, George F. ; Wang, Yu ; Wang, Dayan ; Fan, Ming ; Shu, Yuelong Less -
Description:
Live poultry markets are a source of human infection with avian influenza A (H7N9) virus. On February 21, 2014, a poultry farmer infected with H7N9 virus was identified in Jilin, China, and H7N9 and H9N2 viruses were isolated from the patient's farm. Reassortment between these subtype viruses generated five genotypes, one of which caused the human infection. The date of H7N9 virus introduction to the farm is estimated to be between August 21, 2013 (95% confidence interval [CI] June 6, 2013-October 6, 2013) and September 25, 2013 (95% CI May 28, 2013-January 4, 2014), suggesting that the most likely source of virus introduction was the first batch of poultry purchased in August 2013. The reassortment event that led to the human virus may have occurred between January 2, 2014 (95% CI November 8, 2013-February 12, 2014) and February 12, 2014 (95% CI January 19, 2014-February 18, 2014). Our findings demonstrate that poultry farms could be a source of reassortment between H7N9 virus and H9N2 virus as well as human infection, which emphasizes the importance to public health of active avian influenza surveillance at poultry farms.
Subject:
[+]
Article

Source:
Sci Rep. 2015; 5.
Pubmed ID:
25591105
Pubmed Central ID:
PMC4295517
Document Type:
Journal Article
Funding:
5U51IP000334-03/IP/NCIRD CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:78aa58b95c9d08b977e7027a55d456eb6ab832fbd089b1a538b19055322534b4
File Type:

Supporting Files

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  	srep07630-s1.pdf	pdf
  	srep07630.nxml	txt
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