Mortality Among a Cohort of U.S. Commercial Airline Cockpit Crew
Published Date:Apr 03 2014
Source:Am J Ind Med. 2014; 57(8):906-914.
Cause Of Death
Central Nervous System Neoplasms
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pubmed Central ID:PMC4511278
Funding:DYT1/Intramural CDC HHS/United States
LAY7/Intramural CDC HHS/United States
We evaluated mortality among 5,964 former U.S. commercial cockpit crew (pilots and flight engineers). The outcomes of a priori interest were non-chronic lymphocytic leukemia, central nervous system (CNS) cancer (including brain), and malignant melanoma.
Vital status was ascertained through 2008. Life table and Cox regression analyses were conducted. Cumulative exposure to cosmic radiation was estimated from work history data.
Compared to the U.S. general population, mortality from all causes, all cancer, and cardiovascular diseases was decreased, but mortality from aircraft accidents was highly elevated. Mortality was elevated for malignant melanoma but not for non-chronic lymphocytic leukemia. CNS cancer mortality increased with an increase in cumulative radiation dose.
Cockpit crew had a low all-cause, all-cancer, and cardiovascular disease mortality but elevated aircraft accident mortality. Further studies are needed to clarify the risk of CNS and other radiation-associated cancers in relation to cosmic radiation and other workplace exposures.
You May Also Like: