Mortality Among a Cohort of U.S. Commercial Airline Cockpit Crew

Yong, Lee C.; Pinkerton, Lynne E.; Yiin, James H.; Anderson, Jeri L.; Deddens, James A.

doi:10.1002/ajim.22318

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Mortality Among a Cohort of U.S. Commercial Airline Cockpit Crew

Published Date:

Apr 03 2014

Publisher's site:

http://dx.doi.org/10.1002/ajim.22318

Source:

Am J Ind Med. 2014; 57(8):906-914.

Language:

English

[PDF-226.17 KB]

Details:

Alternative Title:

Am J Ind Med

Personal Author:

Yong, Lee C. ; Pinkerton, Lynne E. ; Yiin, James H. ; Anderson, Jeri L. ; Deddens, James A. ;

Description:

Background We evaluated mortality among 5,964 former U.S. commercial cockpit crew (pilots and flight engineers). The outcomes of a priori interest were non-chronic lymphocytic leukemia, central nervous system (CNS) cancer (including brain), and malignant melanoma. Methods Vital status was ascertained through 2008. Life table and Cox regression analyses were conducted. Cumulative exposure to cosmic radiation was estimated from work history data. Results Compared to the U.S. general population, mortality from all causes, all cancer, and cardiovascular diseases was decreased, but mortality from aircraft accidents was highly elevated. Mortality was elevated for malignant melanoma but not for non-chronic lymphocytic leukemia. CNS cancer mortality increased with an increase in cumulative radiation dose. Conclusions Cockpit crew had a low all-cause, all-cancer, and cardiovascular disease mortality but elevated aircraft accident mortality. Further studies are needed to clarify the risk of CNS and other radiation-associated cancers in relation to cosmic radiation and other workplace exposures.

Subject:

[+]

Pubmed ID:

24700478

Pubmed Central ID:

PMC4511278

Document Type:

Journal Article

Funding:

DYT1/Intramural CDC HHS/United States ; LAY7/Intramural CDC HHS/United States ;

Place as Subject:

United States

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

nihms704829.nxml

text/plain

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