NetworkPainter: dynamic intracellular pathway animation in Cytobank
Published Date:May 25 2015
Source:BMC Bioinformatics. 16(1).
Pubmed Central ID:PMC4491883
Funding:1P50GM107615/GM/NIGMS NIH HHS/United States
5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States
CA125994-01A1/CA/NCI NIH HHS/United States
CA143231/CA/NCI NIH HHS/United States
K99 CA125994/CA/NCI NIH HHS/United States
K99 CA143231/CA/NCI NIH HHS/United States
P50 GM107615/GM/NIGMS NIH HHS/United States
R00 CA125994/CA/NCI NIH HHS/United States
R00 CA143231/CA/NCI NIH HHS/United States
High-throughput technologies such as flow and mass cytometry have the potential to illuminate cellular networks. However, analyzing the data produced by these technologies is challenging. Visualization is needed to help researchers explore this data.
We developed a web-based software program, NetworkPainter, to enable researchers to analyze dynamic cytometry data in the context of pathway diagrams. NetworkPainter provides researchers a graphical interface to draw and “paint” pathway diagrams with experimental data, producing animated diagrams which display the activity of each network node at each time point.
NetworkPainter enables researchers to more fully explore multi-parameter, dynamical cytometry data.
Electronic supplementary material
The online version of this article (doi:10.1186/s12859-015-0602-4) contains supplementary material, which is available to authorized users.
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