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NetworkPainter: dynamic intracellular pathway animation in Cytobank
Filetype[PDF - 1.76 MB]


Details:
  • Pubmed ID:
    26003204
  • Pubmed Central ID:
    PMC4491883
  • Description:
    Background

    High-throughput technologies such as flow and mass cytometry have the potential to illuminate cellular networks. However, analyzing the data produced by these technologies is challenging. Visualization is needed to help researchers explore this data.

    Results

    We developed a web-based software program, NetworkPainter, to enable researchers to analyze dynamic cytometry data in the context of pathway diagrams. NetworkPainter provides researchers a graphical interface to draw and “paint” pathway diagrams with experimental data, producing animated diagrams which display the activity of each network node at each time point.

    Conclusion

    NetworkPainter enables researchers to more fully explore multi-parameter, dynamical cytometry data.

    Electronic supplementary material

    The online version of this article (doi:10.1186/s12859-015-0602-4) contains supplementary material, which is available to authorized users.

  • Document Type:
  • Collection(s):
  • Funding:
    1P50GM107615/GM/NIGMS NIH HHS/United States
    5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States
    CA125994-01A1/CA/NCI NIH HHS/United States
    CA143231/CA/NCI NIH HHS/United States
    K99 CA125994/CA/NCI NIH HHS/United States
    K99 CA143231/CA/NCI NIH HHS/United States
    P50 GM107615/GM/NIGMS NIH HHS/United States
    R00 CA125994/CA/NCI NIH HHS/United States
    R00 CA143231/CA/NCI NIH HHS/United States
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