Details:

Alternative Title:
BMC Bioinformatics
Publisher's site:
http://dx.doi.org/10.1186/s12859-015-0602-4
Personal Author:
Karr, Jonathan R ; Guturu, Harendra ; Chen, Edward Y ; Blair, Stuart L ; Irish, Jonathan M ; ... More +
Karr, Jonathan R ; Guturu, Harendra ; Chen, Edward Y ; Blair, Stuart L ; Irish, Jonathan M ; Kotecha, Nikesh ; Covert, Markus W Less -
Description:
Background

High-throughput technologies such as flow and mass cytometry have the potential to illuminate cellular networks. However, analyzing the data produced by these technologies is challenging. Visualization is needed to help researchers explore this data.

Results

We developed a web-based software program, NetworkPainter, to enable researchers to analyze dynamic cytometry data in the context of pathway diagrams. NetworkPainter provides researchers a graphical interface to draw and “paint” pathway diagrams with experimental data, producing animated diagrams which display the activity of each network node at each time point.

Conclusion

NetworkPainter enables researchers to more fully explore multi-parameter, dynamical cytometry data.

Electronic supplementary material

The online version of this article (doi:10.1186/s12859-015-0602-4) contains supplementary material, which is available to authorized users.


Subject:
[+]
Animation
Cytometry
Network
Software
Systems Biology
Visualization

Source:
BMC Bioinformatics. 16(1).
Pubmed ID:
26003204
Pubmed Central ID:
PMC4491883
Document Type:
Journal Article
Funding:
1P50GM107615/GM/NIGMS NIH HHS/United States ; 5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; CA125994-01A1/CA/NCI NIH HHS/United States ; CA143231/CA/NCI NIH HHS/United States ; K99 CA125994/CA/NCI NIH HHS/United States ; ... More +
1P50GM107615/GM/NIGMS NIH HHS/United States ; 5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; CA125994-01A1/CA/NCI NIH HHS/United States ; CA143231/CA/NCI NIH HHS/United States ; K99 CA125994/CA/NCI NIH HHS/United States ; K99 CA143231/CA/NCI NIH HHS/United States ; P50 GM107615/GM/NIGMS NIH HHS/United States ; R00 CA125994/CA/NCI NIH HHS/United States ; R00 CA143231/CA/NCI NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d60c2b4359b150c017b854b0d78593ff0e6f95895c23d7bd5ae0bde1f3b878cf
File Type:

Supporting Files

• 	license.txt	txt
  	12859_2015_602_Fig1_HTML.gif	gif
  	12859_2015_602_Fig1_HTML.jpg	jpeg
  	12859_2015_602_Fig2_HTML.gif	gif
  	12859_2015_602_Fig2_HTML.jpg	jpeg
  	12859_2015_602_MOESM1_ESM.pdf	pdf
  	12859_2015_Article_602.nxml	txt

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