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Evaluation of influenza vaccine effectiveness and description of circulating strains in outpatient settings in South Africa, 2014
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Jul 2015
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Source: Influenza Other Respir Viruses. 2015; 9(4):209-215.
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Alternative Title:Influenza Other Respir Viruses
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Description:The effectiveness of the trivalent seasonal influenza vaccine during the 2014 season in South Africa was assessed using a test-negative case-control study design including 472 cases and 362 controls. Influenza A(H3N2) was the dominant strain circulating. The overall vaccine effectiveness estimate, adjusted for age and underlying conditions, was 43·1% (95% CI: -26·8-74·5). 2014 H3N2 viruses from South Africa were mainly in sublineage 3C.3 with accumulation of amino acid changes that differentiate them from the vaccine strain in 3C.1.
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Pubmed ID:25865249
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Pubmed Central ID:PMC4474497
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