Details:

Alternative Title:
J Urol
Personal Author:
King, Sallyann Coleman ; Pollack, Lori A. ; Li, Jun ; King, Jessica B. ; Master, Viraj A.
King, Sallyann Coleman ; Pollack, Lori A. ; Li, Jun ; King, Jessica B. ; Master, Viraj A. Less -
Description:
Purpose

More than 50,000 Americans were diagnosed with kidney and renal pelvis cancer in 2010. The National Program of Cancer Registries and SEER (Surveillance, Epidemiology and End Results) combined data include cancer incidences from the entire United States. Our study presents updated incidence data, evaluates trends and adds geographic distribution to the literature.

Materials and Methods

We examined invasive, microscopically confirmed kidney and renal pelvis cancers diagnosed from 2001 to 2010 that met United States Cancer Statistics reporting criteria for each year, excluding cases diagnosed by autopsy or death certificate. Histology codes classified cases as renal cell carcinoma. Rates and trends were estimated using SEER*Stat.

Results

A total of 342,501 renal cell carcinoma cases were diagnosed. The renal cell carcinoma incidence rate increased from 10.6/100,000 individuals in 2001 to 12.4/100,000 in 2010 and increased with age until ages 70 to 74 years. The incidence rate in men was almost double that in women. The annual percent change was higher in women than in men, in those 20 to 24 years old and in grade III tumors.

Conclusions

The annual percent change incidence increased from 2001 to 2010. Asian/Pacific Islanders and 20 to 24-year-old individuals had the highest annual percent change. While some increase resulted from localized disease, the highest annual percent change was in grade III tumors, indicating more aggressive disease. Continued monitoring of trends and epidemiological study are warranted to determine risk factors.


Subject:
[+]
Adolescent
Adult
Aged
Aged, 80 And Over
Age Distribution
Article
Carcinoma, Renal Cell
Child
Child, Preschool
Female
Forecasting
Humans
Incidence
Infant
Infant, Newborn
Kidney Neoplasms
Male
Middle Aged
Neoplasm Staging
Retrospective Studies
SEER Program
Sex Distribution
Survival Rate
Young Adult

Source:
J Urol. 2014; 191(6):1665-1670.
Pubmed ID:
24423441
Pubmed Central ID:
PMC4479175
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:3114c326540bc8d4849d7a6ef65c2a4de4f827203b5df27fda9c7743e7f980c0
File Type:

Supporting Files

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