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The Impact of Case Definition on ADHD Prevalence Estimates in Community-Based Samples of School-Aged Children
Filetype[PDF - 1.06 MB]


Details:
  • Pubmed ID:
    25524790
  • Pubmed Central ID:
    PMC4472453
  • Funding:
    200-2006-18912/PHS HHS/United States
    200-2006-18949/PHS HHS/United States
    CC999999/Intramural CDC HHS/United States
    U50/CCU622315-02/PHS HHS/United States
    U84/CCU422516-02/PHS HHS/United States
  • Document Type:
  • Collection(s):
  • Description:
    Objective

    To determine the impact of varying ADHD diagnostic criteria, including new DSM-5 criteria, on prevalence estimates.

    Method

    Parent and teacher reports identified ADHD high and low screen children from elementary schools in two states that produced a diverse overall sample. The parent interview stage included the Diagnostic Interview Schedule for Children – IV (DISC-IV), and up to four additional follow-up interviews. Weighted prevalence estimates, accounting for complex sampling, quantified the impact of varying ADHD criteria using baseline and the final follow-up interview data.

    Results

    At baseline 1060 caregivers were interviewed; 656 had at least one follow-up interview. Teachers and parents reported six or more ADHD symptoms for 20.5% (95% CI: 18.1%–23.2%) and 29.8% (CI: 24.5%–35.6%) of children respectively, with criteria for impairment and onset by age seven (DSM-IV) reducing these proportions to 16.3% (CI: 14.7%–18.0%) and 17.5% (CI: 13.3%–22.8%); requiring at least four teacher-reported symptoms reduced the parent-reported prevalence to 8.9% (CI: 7.4%–10.6%). Revising age of onset to 12 years per DSM-5 increased this estimate to 11.3% (CI: 9.5%–13.3%), with a similar increase seen at follow-up: 8.2% with age seven onset (CI: 5.9%–11.2%) versus 13.0% (CI: 7.6%–21.4%) with onset by age 12. Reducing the number of symptoms required for those aged 17 and older increased the estimate to 13.1% (CI: 7.7%–21.5%).

    Conclusion

    These findings quantify the impact on prevalence estimates of varying case definition criteria for ADHD. Further research of impairment ratings and data from multiple informants is required to better inform clinicians conducting diagnostic assessments. DSM-5 changes in age of onset and number of symptoms required for older adolescents appear to increase prevalence estimates, although the full impact is uncertain due to the age of our sample.