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The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on behaviour in five-year-old children. A prospective cohort study on 1628 children
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March 21 2013
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Source: BJOG. 120(9):1042-1050
[PDF-206.43 KB]
Details:
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Alternative Title:BJOG
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Personal Author:
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Description:Objective
To examine the effects of low to moderate maternal alcohol consumption and binge drinking in early pregnancy on behaviour in children at age five years.
Design
Follow-up study
Setting
Neuropsychological testing in four Danish cities 2003–2008
Population
Prospective cohort study of 1,628 women and their children sampled from the Danish National Birth Cohort.
Methods
Participants were sampled based on maternal alcohol drinking patterns during early pregnancy. When the children were 5 years old, the Strengths and Difficulties Questionnaire (SDQ) Parent and Teacher versions were completed by the mothers and a preschool teacher. The full statistical model included the following potential confounders: Maternal binge drinking or low-moderate alcohol consumption, respectively, parental education, maternal IQ, prenatal maternal smoking, the child’s age at testing, the child’s gender, maternal age, parity, maternal marital status, family-home environment, postnatal parental smoking, pre-pregnancy maternal BMI, and the child’s health status.
Main outcome measures
Behaviour among children assessed by the SDQ parent and teacher forms.
Results
Adjusted for all potential confounders, no statistically significant associations were observed between maternal low to moderate average weekly alcohol consumption and SDQ behavioural scores (OR 1.1, CI 0.5–2.3 and OR 1.1., CI 0.6–2.1 for the total difficulties scores) or between binge drinking and SDQ behavioural scores (OR 1.2, CI 0.8–1.7 and OR 0.8, CI 0.6–1.2).
Conclusion
This study observed no consistent effects of low to moderate alcohol consumption or binge drinking in early pregnancy on offspring behaviour at age 5 years.
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Subjects:
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Source:
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Pubmed ID:23837773
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Pubmed Central ID:PMC4447188
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Document Type:
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Funding:
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Volume:120
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Issue:9
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