Details:

Alternative Title:
BJOG
Personal Author:
Skogerbø, Åshild ; Kesmodel, Ulrik Schiøler ; Denny, Clark H. ; Kjaersgaard, Maiken Ina Siegismund ; Wimberley, Theresa ; ... More +
Skogerbø, Åshild ; Kesmodel, Ulrik Schiøler ; Denny, Clark H. ; Kjaersgaard, Maiken Ina Siegismund ; Wimberley, Theresa ; Landrø, Nils Inge ; Mortensen, Erik Lykke Less -
Description:
Objective

To examine the effects of low to moderate maternal alcohol consumption and binge drinking in early pregnancy on behaviour in children at age five years.

Design

Follow-up study

Setting

Neuropsychological testing in four Danish cities 2003–2008

Population

Prospective cohort study of 1,628 women and their children sampled from the Danish National Birth Cohort.

Methods

Participants were sampled based on maternal alcohol drinking patterns during early pregnancy. When the children were 5 years old, the Strengths and Difficulties Questionnaire (SDQ) Parent and Teacher versions were completed by the mothers and a preschool teacher. The full statistical model included the following potential confounders: Maternal binge drinking or low-moderate alcohol consumption, respectively, parental education, maternal IQ, prenatal maternal smoking, the child’s age at testing, the child’s gender, maternal age, parity, maternal marital status, family-home environment, postnatal parental smoking, pre-pregnancy maternal BMI, and the child’s health status.

Main outcome measures

Behaviour among children assessed by the SDQ parent and teacher forms.

Results

Adjusted for all potential confounders, no statistically significant associations were observed between maternal low to moderate average weekly alcohol consumption and SDQ behavioural scores (OR 1.1, CI 0.5–2.3 and OR 1.1., CI 0.6–2.1 for the total difficulties scores) or between binge drinking and SDQ behavioural scores (OR 1.2, CI 0.8–1.7 and OR 0.8, CI 0.6–1.2).

Conclusion

This study observed no consistent effects of low to moderate alcohol consumption or binge drinking in early pregnancy on offspring behaviour at age 5 years.


Subject:
[+]
Alcohol Drinking
Article
Behaviour
Binge Drinking
Body Mass Index
Child, Preschool
Child Behavior
Cohort Studies
Denmark
Educational Status
Female
Follow-Up Studies
Health Behavior
Health Education
Health Knowledge, Attitudes, Practice
Humans
Low To Moderate Alcohol Consumption
Male
Maternal Age
Mothers
Neurodevelopmental Effects
Neuropsychological Tests
Pregnancy
Prenatal Exposure Delayed Effects
Prenatal Exposures
Prevalence
Prospective Studies
SDQ
Smoking
Social Class
Social Environment
Strengths And Difficulties Questionnaire
Surveys And Questionnaires

Source:
BJOG. 120(9):1042-1050
Pubmed ID:
23837773
Pubmed Central ID:
PMC4447188
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:90a1a38e51fe758293fc51d38cd0f403cf87544c5364db1b31631a41dc75f62e
File Type:

Supporting Files

• nihms693093.nxml

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