Details:

Alternative Title:
Environ Health Perspect
Publisher's site:
http://dx.doi.org/
Personal Author:
Bradman, Asa ; Fenster, Laura ; Sjödin, Andreas ; Jones, Richard S. ; Patterson, Donald G. ; ... More +
Bradman, Asa ; Fenster, Laura ; Sjödin, Andreas ; Jones, Richard S. ; Patterson, Donald G. ; Eskenazi, Brenda Less -
Description:
Background

Recent studies have raised concerns about polybrominated diphenyl ether (PBDE) flame retardant exposures to pregnant women and women of child-bearing age in the United States. Few studies have measured PBDEs in immigrant populations.

Objectives

Our goal was to characterize levels of seven PBDE congeners, polychlorinated biphenyl (PCB)-153, and polybrominated biphenyl (PBB)-153 in plasma from 24 pregnant women of Mexican descent living in an agricultural community in California.

Results

The median concentration of the sum of the PBDE congeners was 21 ng/g lipid and ranged from 5.3 to 320 ng/g lipid. Consistent with other studies, 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) was found at the highest concentration (median = 11 ng/g lipid; range, 2.5–205) followed by 2,2′,4,4′,5-pentabromobiphenyl (BDE-99) (median = 2.9 ng/g lipid; range, 0.5–54), 2,2′,4,4′,5-pentaBDE (BDE-100) (median = 1.8 ng/g lipid; range, 0.6–44), and 2,2′,4,4′,5,5′-hexaBDE (BDE-153) (median = 1.5 ng/g lipid; range, 0.4–35). Levels of PCB-153 (median= 4.4 ng/g lipid; range, < 2–75) were lower than U.S. averages and uncorrelated with PBDE levels, suggesting different exposure routes.

Conclusions

The overall levels of PBDEs found were lower than levels observed in other U.S. populations, although still higher than those observed previously in Europe or Japan. The upper range of exposure is similar to what has been reported in other U.S. populations. PBDEs have been associated with adverse developmental effects in animals. Future studies are needed to determine the sources and pathways of PBDE exposures and whether these exposures have adverse effects on human health.


Subject:
[+]
Adult
Agriculture
California
Environmental Monitoring
Female
Flame Retardants
Humans
Phenyl Ethers
Polybrominated Biphenyls
Pregnancy
Research

Source:
Environ Health Perspect. 2007; 115(1):71-74.
Document Type:
Journal Article
Funding:
P01 ES009605/ES/NIEHS NIH HHS/United States ; R01 OH007400/OH/NIOSH CDC HHS/United States
P01 ES009605/ES/NIEHS NIH HHS/United States ; R01 OH007400/OH/NIOSH CDC HHS/United States Less -
Place as Subject:
California
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:4bd649a69f78d25b63e3c37fc0a35d3ac570d97f5e6de636d28c7b967ccf5ae5
File Type:

Supporting Files

• 	ehp0115-000071.nxml	txt
  	ehp0115-000071f1.gif	gif
  	ehp0115-000071f1.jpg	jpeg
  	ehp0115-000071f2.gif	gif
  	ehp0115-000071f2.jpg	jpeg
  	license.txt	txt

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