An Upconversion Nanoparticle with Orthogonal Emissions Using Dual NIR Excitations for Controlled Two-way Photoswitching

Lai, Jinping; Zhang, Yixiao; Pasquale, Nicholas; Lee, Ki-Bum

doi:10.1002/anie.201408219

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

An Upconversion Nanoparticle with Orthogonal Emissions Using Dual NIR Excitations for Controlled Two-way Photoswitching

Published Date:

Oct 27 2014

Publisher's site:

http://dx.doi.org/10.1002/anie.201408219 New Site Icon

Source:

Angew Chem Int Ed Engl. 53(52):14419-14423.

[PDF-934.88 KB]

Details:

Personal Authors:

Lai, Jinping ; Zhang, Yixiao ; Pasquale, Nicholas ; Lee, Ki-Bum ;

Keywords:

[+]

Pubmed ID:

25349100

Pubmed Central ID:

PMC4438079

Description:

Developing multicolor upconversion nanoparticles (UCNPs) with the capability of regulating their emission wavelengths in the UV to visible range in response to external stimuli can offer more dynamic platforms for applications in high-resolution bioimaging, multicolor barcoding, and driving multiple important photochemical reactions, such as photoswitching. Here, we have rationally designed single-crystal core-shell-structured UCNPs which are capable of orthogonal UV and visible emissions in response to two distinct NIR excitations at 808 and 980 nm. The orthogonal excitation-emission properties of such UCNPs, as well as their ability to utilize low-power excitation, which attenuates any local heating from the lasers, endows the UCNPs with great potential for applications in materials and biological settings. As a proof of concept, the use of this UCNP for the efficient regulation of the two-way photoswitching of spiropyran by using dual wavelengths of NIR irradiation has been demonstrated.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

1DP20D006462-01/DP/NCCDPHP CDC HHS/United States
1R21NS085569-01/NS/NINDS NIH HHS/United States
DP2 OD006462/OD/NIH HHS/United States
R21 NS085569/NS/NINDS NIH HHS/United States

Supporting Files:

	NIHMS682286-supplement-Supporting_Information.pdf	application/pdf
	nihms682286.nxml	application/octet-stream
	nihms682286f1.gif	image/gif
	nihms682286f1.jpg	image/jpeg
	nihms682286f2.gif	image/gif
	nihms682286f2.jpg	image/jpeg
	nihms682286f3.gif	image/gif
	nihms682286f3.jpg	image/jpeg

No Related Documents.

You May Also Like:

Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles

Personal Author:

Lai, Jinping; Shah, Birju P.; Zhang, Yixiao; Yang, Letao; Lee, Ki-Bum;

Published:

Apr 15 2015

Source:

ACS Nano. 9(5):5234-5245.

Description:

Stimuli-responsive drug delivery vehicles have garnered immense interest in recent years due to unparalleled progress made in material science and nanomedicine. However, the development of stimuli-responsive devices with integrated real-time monitori...

File Type:

[PDF - 1.45 MB]
Design, Synthesis, and Characterization of Graphene–Nanoparticle Hybrid Materials for Bioapplications

Personal Author:

Yin, Perry T.; Shah, Shreyas; Chhowalla, Manish; Lee, Ki-Bum;

Published:

Feb 18 2015

Source:

Chem Rev. 115(7):2483-2531.

File Type:

[PDF - 3.48 MB]
Hybrid Upconversion Nanomaterials for Optogenetic Neuronal Control

Personal Author:

Shah, Shreyas; Liu, Jingjing; Pasquale, Nicholas; Lai, Jinping; McGowan, Heather; Pang, Zhiping P.; Lee, Ki-Bum;

Published:

Oct 28 2015

Source:

Nanoscale. 7(40):16571-16577.

Description:

Nanotechnology-based approaches offer the chemical control required to develop precision tools suitable for applications in neuroscience. We report a novel approach employing hybrid upconversion nanomaterials, combined with the photoresponsive ion ch...

File Type:

[PDF - 1.14 MB]
Multi-scale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe

Personal Author:

Yao, Junjie; Kaberniuk, Andrii A.; Li, Lei; Shcherbakova, Daria M.; Zhang, Ruiying; Wang, Lidai; Li, Guo; Verkhusha, Vladislav V.; Wang, Lihong V.;

Published:

Nov 09 2015

Source:

Nat Methods. 13(1):67-73.

Description:

Photoacoustic tomography (PAT) of genetically encoded probes allows for imaging of targeted biological processes deep in tissues with high spatial resolution; however, high background signals from blood can limit the achievable detection sensitivity....

File Type:

[PDF - 1.52 MB]
Low Power Upconverted Near-IR Light for Efficient Polymeric Nanoparticle Degradation and Cargo Release

Personal Author:

Viger, Mathieu L.; Grossman, Madeleine; Fomina, Nadezda; Almutairi, Adah;

Published:

May 31 2013

Source:

Adv Mater. 25(27):3733-3738.

Description:

By encapsulating NaYF4 :Tm.Yb upconverting nanocrystals in UV-degradable polymer capsules, it is possible to access efficient polymer photodegradation and remotely controlled release using near-IR laser light at an unprecedentedly low power.

File Type:

[PDF - 1.37 MB]