Itaya virus, a Novel Orthobunyavirus Associated with Human Febrile Illness, Peru

Hontz, Robert D.; Guevara, Carolina; Halsey, Eric S.; Silvas, Jesus; Santiago, Felix W.; Widen, Steven G.; Wood, Thomas G.; Casanova, Wilma; Vasilakis, Nikos; Watts, Douglas M.; Kochel, Tadeusz J.; Ebihara, Hideki; Aguilar, Patricia V.

doi:10.3201/eid2105.141368

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Itaya virus, a Novel Orthobunyavirus Associated with Human Febrile Illness, Peru

Published Date:

May 2015

Publisher's site:

http://dx.doi.org/10.3201/eid2105.141368 New Site Icon

Source:

Emerg Infect Dis. 21(5):781-788.

[PDF-1.89 MB]

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Alternative Title:

Emerg Infect Dis

Personal Author:

Hontz, Robert D. ; Guevara, Carolina ; Halsey, Eric S. ; Silvas, Jesus ; Santiago, Felix W. ; ... More ▼

Description:

Our genetic analyses of uncharacterized bunyaviruses isolated in Peru identified a possible reassortant virus containing small and large gene segment sequences closely related to the Caraparu virus and a medium gene segment sequence potentially derived from an unidentified group C orthobunyavirus. Neutralization tests confirmed serologic distinction among the newly identified virus and the prototype and Caraparu strains. This virus, named Itaya, was isolated in 1999 and 2006 from febrile patients in the cities of Iquitos and Yurimaguas in Peru. The geographic distance between the 2 cases suggests that the Itaya virus could be widely distributed throughout the Amazon basin in northeastern Peru. Identification of a new Orthobunyavirus species that causes febrile disease in humans reinforces the need to expand viral disease surveillance in tropical regions of South America.

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

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