25761409

PMC4396622

HHSN261201000034C/PHS HHS/United States
HHSN261201000035C/PHS HHS/United States
HHSN261201000140C/PHS HHS/United States
R01 CA077398/CA/NCI NIH HHS/United States
R01CA77398/CA/NCI NIH HHS/United States
U58DP003862-01/DP/NCCDPHP CDC HHS/United States

CDC Public Access

Purpose

Information on the role of dietary patterns and endometrial cancer risk is limited. We investigated whether dietary patterns are associated with endometrial cancer risk among women in the California Teachers Study cohort.

Methods

Among 75,093 eligible women, 937 developed invasive endometrial cancer between 1995 and 2011. Multivariate Cox regression was performed to estimate relative risks (RR) and 95% confidence intervals (CI) associated with five dietary patterns identified by principal components factor analysis: “plant-based”, “high protein/high fat”, “high carbohydrates”, “ethnic”, and “salad and wine”.

Results

These dietary patterns were not associated with endometrial cancer risk overall (RR=0.91, 95% CI: 0.72, 1.15 for the highest vs. lowest quintile of the “plant-based” dietary pattern) or by menopausal status and hormone therapy use.

Conclusions

Dietary patterns do not seem to be associated with endometrial cancer risk.