Hospital costs associated with atrial fibrillation for ischemic stroke patients aged 18-64 years in the United States

Details

• Alternative Title:
  Stroke
• Personal Author:
  Wang, Guijing ; Joo, Heesoo ; Tong, Xin ; George, Mary G.
• Description:
  Background and purpose
  
  Hospital costs associated with atrial fibrillation (AFib) among stroke patients have not been well-studied, especially among people younger than 65 years. We estimated the AFib-associated hospital costs in U.S. patients aged 18-64 years.
  
  Methods
  
  We identified hospital admissions with a primary diagnosis of ischemic stroke from the 2010-2012 MarketScan Commercial Claims and Encounters inpatient datasets, excluding those with capitated health insurance plans, aged <18 or >64, missing geographic region, hospital costs below the 1st or above 99th percentile, and having carotid intervention (N=40,082). We searched the data for AFib and analyzed the costs for non-repeat and repeat stroke admissions separately. We estimated the AFib-associated costs using multivariate regression models controlling for age, sex, geographic region, and Charlson comorbidity index.
  
  Results
  
  Of the 33,500 non-repeat stroke admissions, 2,407 (7.2%) had AFib. Admissions with AFib cost $4,991 more than those without AFib ($23,770 vs. $18,779). For the 6,582 repeat stroke admissions, 397 (6.0%) had AFib. The costs were $3,260 more for those with AFib than those without ($24,119 vs. $20,929). After controlling for potential confounders, AFib-associated costs for non-repeat stroke admissions were $4,905, representing 20.6% of the total costs for the admissions. Both the hospital costs and the AFib-associated costs were associated with age, but not sex. AFib-associated costs for repeat stroke admissions were not significantly higher than for non-AFib patients, except for those aged 55-64 ($3,537).
  
  Conclusions
  
  AFib increased the hospital cost of ischemic stroke substantially. Further investigation on AFib-associated costs for repeat stroke admissions is needed.
  
  
• Keywords:
  Adolescent Adult Age Factors Atrial Fibrillation Brain Ischemia Female Hospital Admission Hospital Cost Hospital Costs Hospitalization Humans International Classification Of Diseases Ischemic Stroke Male Middle Aged Recurrence Stroke United States Young Adult

  More +
• Source:
  Stroke. 46(5):1314-1320
• Pubmed ID:
  25851767
• Pubmed Central ID:
  PMC4414908
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  46
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c45ed46e6400b5ca90464e789370e9499d016c9a5233412c2e04a9f517600259
• Download URL:
  https://stacks.cdc.gov/view/cdc/30750/cdc_30750_DS1.pdf
• File Type:
  [PDF - 234.47 KB ]