Lack of Evidence for Human-to-Human Transmission of Avian Influenza A (H9N2) Viruses in Hong Kong, China 19991

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Uyeki, Timothy M. ; Chong, Yu-Hoi ; Katz, Jacqueline M. ; Lim, Wilina ; Ho, Yuk-Yin ; Wang, Sophia S. ; Tsang, Thomas H.F. ; Au, Winnie Wan-Yee ; Chan, Shuk-Chi ; Rowe, Thomas ; Hu-Primmer, Jean ; Bell, Jensa C. ; Thompson, William W. ; Bridges, Carolyn Buxton ; Cox, Nancy J. ; Mak, Kwok-Hang ; Fukuda, Keiji
• Description:
  In April 1999, isolation of avian influenza A (H9N2) viruses from humans was confirmed for the first time. H9N2 viruses were isolated from nasopharyngeal aspirate specimens collected from two children who were hospitalized with uncomplicated, febrile, upper respiratory tract illnesses in Hong Kong during March 1999. Novel influenza viruses have the potential to initiate global pandemics if they are sufficiently transmissible among humans. We conducted four retrospective cohort studies of persons exposed to these two H9N2 patients to assess whether human-to-human transmission of avian H9N2 viruses had occurred. No serologic evidence of H9N2 infection was found in family members or health-care workers who had close contact with the H9N2-infected children, suggesting that these H9N2 viruses were not easily transmitted from person to person.
• Subjects:
  Animals Antibodies, Viral Birds Child, Preschool Cohort Studies Disease Transmission, Infectious Female Humans Infant Infectious Disease Transmission, Patient-To-Professional Influenza A Virus Influenza A Virus, H9N2 Subtype Influenza In Birds Research Retrospective Studies

  More +
• Source:
  Emerg Infect Dis. 8(2):154-159.
• Document Type:
  Journal Article
• Place as Subject:
  Hong Kong
• Location:
  Asia
• Volume:
  8
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0c296e6cfafe044a16e25808f5ee1ca7d936388100c2fc09656ba7d783fc1ba4
• Download URL:
  https://stacks.cdc.gov/view/cdc/3069/cdc_3069_DS1.pdf
• File Type:
  [PDF - 62.61 KB ]