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Combined magnetic nanoparticle-based microRNA and hyperthermia therapy to enhance apoptosis in brain cancer cells
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June 20 2014
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Source: Small. 10(20):4106-4112
[PDF-662.26 KB]
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Alternative Title:Small
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Description:A novel therapy is demonstrated utilizing magnetic nanoparticles for the dual purpose of delivering microRNA and inducing magnetic hyperthermia. In particular, the combination of lethal-7a microRNA (let-7a), which targets a number of the survival pathways that typically limit the effectiveness of hyperthermia, with magnetic hyperthermia greatly enhances apoptosis in brain cancer cells.
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Pubmed ID:24947843
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Pubmed Central ID:PMC4206574
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Volume:10
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Issue:20
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