Details:

Alternative Title:
Angew Chem Int Ed Engl
Publisher's site:
http://dx.doi.org/10.1002/anie.201405355
Personal Author:
Yamazoe, Sayumi ; Liu, Qingyang ; McQuade, Lindsey E. ; Deiters, Alexander ; Chen, James K.
Yamazoe, Sayumi ; Liu, Qingyang ; McQuade, Lindsey E. ; Deiters, Alexander ; Chen, James K. Less -
Description:
Spectrally differentiated caged morpholino oligonucleotides (cMOs) and wavelength-selective illumination have been used to sequentially inactivate organismal gene function. The efficacy of these reverse-genetic chemical probes has been demonstrated in zebrafish embryos, and these reagents have been employed to examine the mechanisms of mesoderm patterning.
Subjects:
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Amino Acid Sequence Animals Antisense Oligonucleotides Article Caged Compounds Developmental Biology Gene Expression Gene Silencing Molecular Structure Morpholinos Zebrafish
Source:
Angew Chem Int Ed Engl. 2013; 53(38):10114-10118.
Pubmed ID:
25130695
Pubmed Central ID:
PMC4206551
Document Type:
Journal Article
Funding:
DP1 HD075622/DP/NCCDPHP CDC HHS/United States ; P50 GM107615/GM/NIGMS NIH HHS/United States ; R01 GM079114/GM/NIGMS NIH HHS/United States ; R01 GM079114/GM/NIGMS NIH HHS/United States ; R01 GM087292/GM/NIGMS NIH HHS/United States ; ... More +
DP1 HD075622/DP/NCCDPHP CDC HHS/United States ; P50 GM107615/GM/NIGMS NIH HHS/United States ; R01 GM079114/GM/NIGMS NIH HHS/United States ; R01 GM079114/GM/NIGMS NIH HHS/United States ; R01 GM087292/GM/NIGMS NIH HHS/United States ; R21 HD078385/HD/NICHD NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:daff239b6094cded8b740436ff35c7a45e3ee7fe959184103fcbc05b9228c22a
Download URL:
https://stacks.cdc.gov/view/cdc/30151/cdc_30151_DS1.pdf
File Type:

Supporting Files

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