Details:

Alternative Title:
Angew Chem Int Ed Engl
Publisher's site:
http://dx.doi.org/10.1002/anie.201405355
Personal Author:
Yamazoe, Sayumi; Liu, Qingyang; McQuade, Lindsey E.; Deiters, Alexander; Chen, James K.;
Yamazoe, Sayumi; Liu, Qingyang; McQuade, Lindsey E.; Deiters, Alexander; Chen, James K.; Less -
Description:
Spectrally differentiated caged morpholino oligonucleotides (cMOs) and wavelength-selective illumination have been used to sequentially inactivate organismal gene function. The efficacy of these reverse-genetic chemical probes has been demonstrated in zebrafish embryos, and these reagents have been employed to examine the mechanisms of mesoderm patterning.
Subject:
[+]
Amino Acid Sequence
Animals
Antisense Oligonucleotides
Article
Caged Compounds
Developmental Biology
Gene Expression
Gene Silencing
Molecular Structure
Morpholinos
Zebrafish
Zebrafish

Source:
Angew Chem Int Ed Engl. 2013; 53(38):10114-10118.;
Pubmed ID:
25130695
Pubmed Central ID:
PMC4206551
Document Type:
Journal Article;
Funding:
DP1 HD075622/DP/NCCDPHP CDC HHS/United States; P50 GM107615/GM/NIGMS NIH HHS/United States; R01 GM079114/GM/NIGMS NIH HHS/United States; R01 GM079114/GM/NIGMS NIH HHS/United States; R01 GM087292/GM/NIGMS NIH HHS/United States; ... More +
DP1 HD075622/DP/NCCDPHP CDC HHS/United States; P50 GM107615/GM/NIGMS NIH HHS/United States; R01 GM079114/GM/NIGMS NIH HHS/United States; R01 GM079114/GM/NIGMS NIH HHS/United States; R01 GM087292/GM/NIGMS NIH HHS/United States; R21 HD078385/HD/NICHD NIH HHS/United States; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:daff239b6094cded8b740436ff35c7a45e3ee7fe959184103fcbc05b9228c22a
File Type:

Supporting Files

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