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Sequential Gene Silencing Using Wavelength-Selective Caged Morpholinos**
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Published Date:
Aug 01 2014
Publisher's site:Source:Angew Chem Int Ed Engl. 2013; 53(38):10114-10118.
[PDF-795.37 KB]
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Alternative Title:Angew Chem Int Ed Engl
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Description:Spectrally differentiated caged morpholino oligonucleotides (cMOs) and wavelength-selective illumination have been used to sequentially inactivate organismal gene function. The efficacy of these reverse-genetic chemical probes has been demonstrated in zebrafish embryos, and these reagents have been employed to examine the mechanisms of mesoderm patterning.
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Subject:
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Pubmed ID:25130695
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Pubmed Central ID:PMC4206551
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