Welcome to CDC stacks | Absolute Photoacoustic Thermometry in Deep Tissue - 29836 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Absolute Photoacoustic Thermometry in Deep Tissue
  • Published Date:
    Dec 15 2013
  • Source:
    Opt Lett. 2013; 38(24):5228-5231.
Filetype[PDF-663.92 KB]


Details:
  • Personal Authors:
  • Keywords:
  • Pubmed ID:
    24322224
  • Pubmed Central ID:
    PMC3901074
  • Description:
    Photoacoustic thermography is a promising tool for temperature measurement in deep tissue. Here we propose an absolute temperature measurement method based on the dual temperature dependences of the Grüneisen parameter and the speed of sound in tissue. By taking ratiometric measurements at two adjacent temperatures, we can eliminate the factors that are temperature irrelevant but difficult to correct for in deep tissue. To validate our method, absolute temperatures of blood-filled tubes embedded ~9 mm deep in chicken tissue were measured in a biologically relevant range from 28°C to 46°C. The temperature measurement accuracy was ~0.6°C. The results suggest that our method can be potentially used for absolute temperature monitoring in deep tissue during thermotherapy.

  • Document Type:
    Journal Article
  • Collection(s):
    CDC Public Access
  • Funding:
    DP1 EB016986/DP/NCCDPHP CDC HHS/United States
    DP1 EB016986/EB/NIBIB NIH HHS/United States
    R01 CA134539/CA/NCI NIH HHS/United States
    R01 CA134539/CA/NCI NIH HHS/United States
    R01 CA157277/CA/NCI NIH HHS/United States
    R01 CA157277/CA/NCI NIH HHS/United States
    R01 CA159959/CA/NCI NIH HHS/United States
    R01 CA159959/CA/NCI NIH HHS/United States
    R01 EB008085/EB/NIBIB NIH HHS/United States
    R01 EB008085/EB/NIBIB NIH HHS/United States
    T32 EB014855/EB/NIBIB NIH HHS/United States
    U54 CA136398/CA/NCI NIH HHS/United States
    U54 CA136398/CA/NCI NIH HHS/United States
No Related Documents.
You May Also Like:
  1. Photoacoustic microscopy and computed tomography: from bench to bedside
    Personal Author:
    Wang, Lihong V.; Gao, Liang;
    Published:
    May 28 2014
    Source:
    Annu Rev Biomed Eng. 16:155-185.
    Description:
    Photoacoustic imaging (PAI) of biological tissue has seen immense growth in the past decade, providing unprecedented spatial resolution and functional information at depths in the optical diffusive regime. PAI uniquely combines the advantages of opti...
    File Type:
    Filetype[PDF - 2.92 MB]
  2. Spatially Fourier-encoded photoacoustic microscopy using a digital micromirror device
    Personal Author:
    Liang, Jinyang; Gao, Liang; Li, Chiye; Wang, Lihong V.;
    Published:
    Feb 1 2014
    Source:
    Opt Lett. 2013; 39(3):430-433.
    Description:
    We have developed spatially Fourier-encoded photoacoustic (PA) microscopy using a digital micromirror device. The spatial intensity distribution of laser pulses is Fourier-encoded, and a series of such encoded PA measurements allows one to decode the...
    File Type:
    Filetype[PDF - 1.95 MB]
  3. Multi-scale Functional and Molecular Photoacoustic Tomography
    Personal Author:
    Yao, Junjie; Xia, Jun; Wang, Lihong V.;
    Published:
    May 01 2015
    Source:
    Ultrason Imaging. 38(1):44-62.
    Description:
    Photoacoustic tomography (PAT) combines rich optical absorption contrast with the high spatial resolution of ultrasound at depths in tissue. The high scalability of PAT has enabled anatomical imaging of biological structures ranging from organelles t...
    File Type:
    Filetype[PDF - 1.03 MB]
  4. Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals
    Personal Author:
    Xia, Jun; Danielli, Amos; Liu, Yan; Wang, Lidai; Maslov, Konstantin; Wang, Lihong V.;
    Published:
    Aug 1 2013
    Source:
    Opt Lett. 2010; 38(15):2800-2803.
    Description:
    Photoacoustic tomography (PAT) is a hybrid imaging technique that has broad preclinical and clinical applications. Based on the photoacoustic effect, PAT directly measures specific optical absorption, which is the product of the tissue-intrinsic opti...
    File Type:
    Filetype[PDF - 624.33 KB]
  5. Small-animal whole-body photoacoustic tomography: a review
    Personal Author:
    Xia, Jun; Wang, Lihong V.;
    Published:
    Sep 25 2013
    Source:
    IEEE Trans Biomed Eng. 2013; 61(5):1380-1389.
    Description:
    With the wide use of small animals for biomedical studies, in vivo small-animal whole-body imaging plays an increasingly important role. Photoacoustic tomography (PAT) is an emerging whole-body imaging modality that shows great potential for preclini...
    File Type:
    Filetype[PDF - 1.66 MB]