Anal Cancer Incidence and Mortality in Puerto Rico
Published Date:Jun 2013
Source:P R Health Sci J. 32(2):76-81.
African Continental Ancestry Group
Aged, 80 And Over
European Continental Ancestry Group
Pubmed Central ID:PMC3770822
Funding:1R03DA031590-01/DA/NIDA NIH HHS/United States
DP000782-04/DP/NCCDPHP CDC HHS/United States
R03 DA027939/DA/NIDA NIH HHS/United States
R03 DA027939-01/DA/NIDA NIH HHS/United States
R03 DA031590/DA/NIDA NIH HHS/United States
U54 CA096297/CA/NCI NIH HHS/United States
U54CA96297/CA/NCI NIH HHS/United States
U54CA96300/CA/NCI NIH HHS/United States
Anal cancer is a rare tumor that is associated with oncogenic HPV genotypes. This study aims to compare the age-standardized rates (ASRs) of anal cancer incidence and mortality in men and women living in Puerto Rico (PR) with those of non-Hispanic whites (NHW), non-Hispanic blacks (NHB), and Hispanics (USH) living in the continental United States (US).
ASRs were calculated based on cancer data that came from the PR Cancer Central Registry and from the Surveillance, Epidemiology, and End Results (SEER) program. The age-specific relative risks (RR) and 95% Confidence Interval (95% CI) were estimated using Poisson regression models.
Comparing the period of 2001 to 2004 to that of 1992 to 1996, the incidence of anal cancer increased among NHW, NHB, and PR men. In females, an increase in the incidence was observed for all racial groups except for Puerto Rican women. When evaluating findings by age groups, Puerto Rican men younger than 60 years old had a 20% higher incidence of anal cancer than did USH men of the same age strata (RR: 2.20; 95% CI = 1.48–3.29). However, Puerto Rican females had a lower incidence of anal cancer than NHW and NHB women. An increased percent change in mortality was observed only in NHW and NHB men. A decreasing trend was observed in all racial/ethnic groups except for NHW women.
Our results support the notion that there are racial/ethnic differences in anal cancer incidence and mortality, with potential disparities among men and women in PR compared with USH men and women. Given the increasing incidence trends in anal cancer, particularly among PR, NHW, and NHB men, further investigation is needed to better elucidate screening practices that can aid in the prevention of anal cancer.
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