Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2103.140634
Personal Author:
Navarro-Torné, Adoración ; Dias, Joana Gomes ; Hruba, Frantiska ; Lopalco, Pier Luigi ; Pastore-Celentano, Lucia ; ... More +
Navarro-Torné, Adoración ; Dias, Joana Gomes ; Hruba, Frantiska ; Lopalco, Pier Luigi ; Pastore-Celentano, Lucia ; Gauci, Andrew J. Amato ; Less -
Corporate Authors:
Invasive Pneumococcal Disease Study Group ;
Description:
We studied the possible association between patient age and sex, clinical presentation, Streptococcus pneumoniae serotype, antimicrobial resistance, and death in invasive pneumococcal disease cases reported by 17 European countries during 2010. The study sample comprised 2,921 patients, of whom 56.8% were men and 38.2% were >65 years of age. Meningitis occurred in 18.5% of cases. Death was reported in 264 (9.0%) cases. Older age, meningitis, and nonsusceptibility to penicillin were significantly associated with death. Non-pneumococcal conjugate vaccine (PCV) serotypes among children <5 years of age and 7-valent PCV serotypes among persons 5-64 years of age were associated with increased risk for death; among adults >65 years of age, risk did not differ by serotype. These findings highlight differences in case-fatality rates between serotypes and age; thus, continued epidemiologic surveillance across all ages is crucial to monitor the long-term effects of PCVs.
Subject:
[+]
Antimicrobial Drug Resistance
Bacteria
Death
Europe
Invasive Pneumococcal Disease
Meningitis
Pneumococcal Vaccine
Research
Risk Factors For Death From Invasive Pneumococcal Disease, Europe, 2010
Streptococcus Pneumonia

Source:
Emerg Infect Dis. 21(3):417-425.
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:739f270e8b3f47b2f8ae130cdce0dd2345ce827bd27e92e039588cedd083180f
File Type:

Supporting Files

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