National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Vector-Borne Diseases.

Atypical and severe manifestations • Although most chikungunya virus infections result in fever and arthralgia, other clinical manifestations can occur. • Atypical or severe clinical manifestations can be due to the direct effects of the virus, immunologic response to the virus, drug toxicity, or diseases unrelated to chikungunya virus infection. • Some atypical or severe manifestations are more common in certain groups. For example, vesiculobullous lesions, febrile seizures, and meningoencephalitis have been reported in infants and young children. • Since many atypical and severe clinical manifestations will be unrelated to chikungunya virus infection, healthcare providers should consider and evaluate for other etiologies.

Pamphlet (or booklet)

Stephen B. Thacker CDC Library collection