Welcome to CDC Stacks | Fighting a deadly fungus : a new strategy to reduce deaths due to Cryptococcus - 26313 | Stephen B. Thacker CDC Library collection
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Fighting a deadly fungus : a new strategy to reduce deaths due to Cryptococcus
  • Published Date:
    May 2011
  • Language:
    English
Filetype[PDF - 1.17 MB]


Details:
  • Corporate Authors:
    National Center for Emerging & Zoonotic Infectious Diseases (U.S.). Division of Foodborne, Waterborne, and Environmental Diseases,
  • Description:
    Cryptococcal meningitis is a leading cause of death among people living with HIV. In sub-Saharan Africa, it is estimated to kill more people than tuberculosis.

    Cryptococcus is a fungus that is found in the soil and produces spores that can be inhaled. People can get Cryptococcus early in life but never know it. If a person’s immune system is weakened (for example, by HIV), Cryptococcus can cause a life-threatening infection called cryptococcal meningitis.

    Why is Cryptococcus a major public health issue?

    • It is a leading cause of death among people living with HIV.

    • Cryptococcus is the most common cause of meningitis in Africa. Meningitis develops after the dormant fungus has been reactivated. For people living with HIV, it can be triggered when their CD4+ count drops.

    • Cryptococcal meningitis mortality is high (50–70%).

    • In developing countries, medication to treat cryptococcal meningitis is often unavailable or too expensive.

    • Management of cryptococcal meningitis is intensive, requiring frequent lumbar punctures and lifelong medication.

    Cryptococcus: A call to action

    By 2015, equip one-half of all HIV clinics in Africa and Asia to perform Cryptococcus testing and treatment. This could save 50,000–100,000 lives each year.

    CS220776A

  • Supporting Files:
    No Additional Files