Association of Contrast Sensitivity With Eye Disease and Vision-Related Quality of Life.

Details

• Alternative Title:
  American Journal of Ophthalmology, 2024, v. 261: Association of Contrast Sensitivity With Eye Disease and Vision-Related Quality of Life.
• Journal Article:
  American Journal of Ophthalmology
• Personal Author:
  Flaharty, Kathryn ; Niziol, Leslie M. ; Woodward, Maria A. ; Elam, Angela ; Bicket, Amanda ; Killeen, Olivia J. ; Zhang, Jason ; Johnson, Leroy ; Kershaw, Martha ; John, Denise A. ; Wood, Sarah K. ; Musch, David C. ; Newman-Casey, Paula Anne
• Description:
  To investigate contrast sensitivity (CS) as a screening tool to detect eye disease and assess its association with both eye disease and vision-related quality of life.
  
  Cross-sectional study.
  
  Setting and population: Adults receiving care from a free clinic and a Federally Qualified Health Center in Michigan.
  
  Screening positive for eye disease and Visual Function Questionnaire (VFQ) score.
  
  Participants received a vision exam reviewed via telemedicine for disease, completed a demographic survey, and the 9-item VFQ. The ability of CS to predict eye disease was explored and area under the curve (AUC) is reported. Logistic and linear regression were used to investigate the continuous effect of CS on the probability of screening positive for eye disease and VFQ score, respectively, adjusting for age and visual acuity.
  
  1159 included participants were, on average, 54.9 ± 14.5 years old, 62% identified as female, 34% as White, 54% as Black, 10% as Hispanic/Latino, and reported mean VFQ score of 79.7 ± 15.3. CS ranged from 0.00 to 1.95 log units (mean = 1.54 ± 0.24), 21% of eyes had glaucoma, 19% cataract, 6% DR, and 2% AMD. AUCs were 0.53 to 0.73. A 0.3 log unit decrease in better eye CS was associated with increased odds of glaucoma (odds ratio OR = 1.35, confidence interval CI = 1.09-1.67), cataract (OR = 1.35, CI = 1.05-1.72), DR (OR = 2.05, CI = 1.51-2.77), and AMD (OR = 2.08, CI = 1.10-3.91). A 0.3 log unit increase in better eye CS was associated with a 5.9 unit increase in VFQ.
  
  While CS alone is not sufficient to identify people with eye disease, it is an important measure of visual function that can add value to comprehensive eye screening.
• Content Notes:
  Author manuscript
• Subjects:
  • Adult
  • Humans
  • Female
  • Middle Aged
  • Aged
  • Quality of Life
  • Contrast Sensitivity
  • Cross-Sectional Studies
  • Cataract
  • Glaucoma
  More +
• Keywords:
  • contrast sensitivity
  • vision-related quality of life
  • glaucoma
  • telemedicine
  • visual function
• Source:
  American Journal of Ophthalmology, 2024, v. 261
• DOI:
  https://doi.org/10.1016/j.ajo.2024.01.021
• ISSN:
  0002-9394 ; 1879-1891
• Pubmed ID:
  38281569
• Pubmed Central ID:
  PMC12001291
• Document Type:
  Text
• Funding:
  R21 AG080407/AG/NIA NIH HHSUnited States/ ; R01 EY031337/EY/NEI NIH HHSUnited States/ ; R01 EB032328/EB/NIBIB NIH HHSUnited States/ ; U01 DP006442/DP/NCCDPHP CDC HHSUnited States/ ; P30 EY007003/EY/NEI NIH HHSUnited States/ ; K23 MD016430/MD/NIMHD NIH HHSUnited States/ ; K12 EY015025/EY/NEI NIH HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  176-186 (18 pdf pages)
• Volume:
  261
• Download URL:
  https://stacks.cdc.gov/view/cdc/262138/cdc_262138_DS1.pdf
• File Type:
  [PDF - 276.00 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:36e12dae691c67c277341f419cf03e2a6dcd75a7e829ad4e951ef4fb86b7c71b471f7efd6283d8ba74db1a8575cb3396dedcb747e2986f68fea2b477d4a0a921