Clusters of Emerging Multidrug-resistant Organisms in US Health Care Facilities During the Initial Months of the SARS-CoV-2 Pandemic.

Details

• Alternative Title:
  American Journal of Infection Control, 2024, v. 52, no. 12: Clusters of Emerging Multidrug-resistant Organisms in US Health Care Facilities During the Initial Months of the SARS-CoV-2 Pandemic.
• Journal Article:
  American Journal of Infection Control
• Personal Author:
  Ham, D. Cal ; Li, Ruoran ; Mitsunaga, Tisha ; Czaja, Christopher ; Prestel, Christopher ; Bhaurla, Sandeep ; Cumming, Melissa ; Brennan, Brenda ; Innes, Gabriel ; Carrico, Savannah ; Chan, Allison ; Merengwa, Enyinnaya ; Stahl, Anna ; Ostrowsky, Belinda ; de Perio, Marie A. ; Walters, Maroya Spalding
• Description:
  Outbreaks of emerging multidrug-resistant organisms (eMDROs), including carbapenem-resistant Enterobacterales, carbapenem-resistant Acinetobacter baumannii, and Candida auris, have been reported among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. We describe eMDRO clusters in SARS-CoV-2 units and associated infection control (IC) practices early in the SARS-CoV-2 pandemic.
  
  We conducted a retrospective survey of a convenience sample of health departments in 11 states to describe clusters of eMDROs that began before November 1, 2020 and involved SARS-CoV-2 units. Cluster characteristics and IC practices during the cluster period were assessed using a standardized outbreak report form, and descriptive analyses were performed.
  
  Overall, 18 eMDRO clusters (10 carbapenem-resistant Enterobacterales, 6 C auris, 1 carbapenem-resistant Pseudomonas aeruginosa, and 1 carbapenem-resistant A baumannii) in 18 health care facilities involving 397 patients were reported from 10 states. During the cluster period, 60% of facilities reported a shortage of isolation gowns, 69% extended use of gowns, and 67% reported difficulty obtaining preferred disinfectants. Reduced frequency of hand hygiene audits was reported in 85% of acute care hospitals during the cluster period compared with before the pandemic.
  
  Changes in IC practices and supply shortages were identified in facilities with eMDRO outbreaks during the SARS-CoV-2 pandemic and might have contributed to eMDRO transmission.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • COVID-19
  • Retrospective Studies
  • Health Facilities
  • SARS-CoV-2
  • Infection Control
  • Drug Resistance, Multiple, Bacterial
  • Cross Infection
  • Acinetobacter baumannii
  • Candida auris
  More +
• Keywords:
  • Outbreaks
  • COVID-19
  • Infection control
• Source:
  American Journal of Infection Control, 2024, v. 52, no. 12
• DOI:
  https://doi.org/10.1016/j.ajic.2024.07.013
• ISSN:
  0196-6553 ; 1527-3296
• Pubmed ID:
  39089494
• Pubmed Central ID:
  PMC11771245
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  1390-1396 (15 pdf pages)
• Volume:
  52
• Issue:
  12
• Download URL:
  https://stacks.cdc.gov/view/cdc/262066/cdc_262066_DS1.pdf
• File Type:
  [PDF - 237.43 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:d76dc078b7fb73e3b3d7071f5cb9fe05b86402516ce660da322e6c6d12f9c389ac4700fd855f696c747469e371ab7433a0644cfccc34368fcdb0be9f69fe397c