Impact of Age of Sexual Debut on HIV Care Engagement Among Sexual and Gender Minorities in Nigeria.

Details

• Alternative Title:
  Journal of Acquired Immune Deficiency Syndromes (1999), 2025, v. 98, no. 3: Impact of Age of Sexual Debut on HIV Care Engagement Among Sexual and Gender Minorities in Nigeria.
• Journal Article:
  Journal of Acquired Immune Deficiency Syndromes (1999)
• Personal Author:
  Volpi, Connor ; Adebiyi, Ruxton ; Chama, John ; Ononaku, Uche ; Aka, Abayomi ; Mitchell, Andrew ; Shutt, Ashley ; Kokogho, Afoke ; Tiamiyu, Abdulwasiu B. ; Baral, Stefan D. ; Charurat, Man ; Adebajo, Sylvia ; Crowell, Trevor A. ; Nowak, Rebecca G.
• Description:
  Sexual and gender minorities (SGM) bear a high burden of HIV. The age of anal sexual debut may influence HIV care engagement. Our objective was to evaluate this relationship to help health care providers promote and anticipate future HIV care engagement among at-risk SGM.
  
  The TRUST/RV368 study provided HIV testing and treatment at SGM-friendly clinics in Abuja and Lagos, Nigeria. Self-reported age of sexual debut was dichotomized as <16 or ≥16 years. Multivariable logistic models estimated adjusted odds ratios (aOR) and 95% confidence intervals (CI) for the association of sexual debut with (1) HIV testing history, (2) HIV testing at the clinics, (3) initiation of antiretroviral therapy (ART) within 6 months of a clinic diagnosis, and (4) viral suppression within 12 months of ART initiation.
  
  Of the 2680 participants, 30% (n = 805) reported a sexual debut <16 years. Those with an <16-year debut had significantly more receptive sex partners, condomless sex, and transactional sex (all P < 0.01) and were 24% less likely to have tested for HIV before enrollment (aOR: 0.76; CI: 0.62 to 0.93). However, <16-year debut was not associated with HIV testing, receiving ART, or achieving viral suppression once engaged with TRUST/RV368 (all P > 0.05).
  
  SGM with <16-year debut engaged in behaviors that could increase HIV risk and were less likely to have a history of HIV testing. However, once enrolled in SGM-friendly clinics, uptake of HIV care was not associated with <16-year debut, suggesting that SGM-friendly care models may promote HIV care engagement.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • HIV Infections
  • Male
  • Female
  • Adult
  • Sexual Behavior
  • Young Adult
  • Adolescent
  • Sexual and Gender Minorities
  • Middle Aged
  More +
• Source:
  Journal of Acquired Immune Deficiency Syndromes (1999), 2025, v. 98, no. 3
• DOI:
  https://doi.org/10.1097/QAI.0000000000003574
• ISSN:
  1525-4135 ; 1944-7884
• Pubmed ID:
  39630093
• Pubmed Central ID:
  PMC12284927
• Document Type:
  Text
• Funding:
  R01 MH099001/MH/NIMH NIH HHSUnited States/ ; K07CA225403/CA/NCI NIH HHSUnited States/ ; NU2GGH002099/CC/CDC HHSUnited States/ ; D43 TW010051/TW/FIC NIH HHSUnited States/ ; 5T32CA009314-40/CA/NCI NIH HHSUnited States/ ; T32 CA009314/CA/NCI NIH HHSUnited States/ ; D43TW010051/TW/FIC NIH HHSUnited States/ ; R01 MH110358/MH/NIMH NIH HHSUnited States/ ; W81XWH-18-2-0040/Henry M. Jackson Foundation/ ; K07 CA225403/CA/NCI NIH HHSUnited States/ ; W81XWH-11-2-0174/Henry M. Jackson Foundation/ ; R01 AI120913/AI/NIAID NIH HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  Nigeria
• Pages in Document:
  242-251 (20 pdf pages)
• Volume:
  98
• Issue:
  3
• Download URL:
  https://stacks.cdc.gov/view/cdc/261887/cdc_261887_DS1.pdf
• File Type:
  [PDF - 182.77 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:748acfa07fb767d96d818629c7fd20b263486f290f036552b610a55575ff7ef1da6f9c326f804798a032869ebb038be002876e6c6108939d38555b0fa0a125f6