The Alcohol Exposome.

Details

• Alternative Title:
  Alcohol (Fayetteville, N.Y.), 2025, v. 122: The Alcohol Exposome.
• Journal Article:
  Alcohol (Fayetteville, N.Y.)
• Personal Author:
  Sabet, Nousha H. ; Wyatt, Todd A.
• Description:
  Science is now in a new era of exposome research that strives to build a more all-inclusive, panoramic view in the quest for answers; this is especially true in the field of toxicology. Alcohol exposure researchers have been examining the multivariate co-exposures that may either exacerbate or initiate alcohol-related tissue/organ injuries. This manuscript presents selected key variables that represent the Alcohol Exposome. The primary variables that make up the Alcohol Exposome can include comorbidities such as cigarettes, poor diet, occupational hazards, environmental hazards, infectious agents, and aging. In addition to representing multiple factors, the Alcohol Exposome examines the various types of intercellular communications that are carried from one organ system to another and may greatly impact the types of injuries and metabolites caused by alcohol exposure. The intent of defining the Alcohol Exposome is to bring the newly expanded definition of Exposomics, meaning the study of the exposome, to the field of alcohol research and to emphasize the need for examining research results in a non-isolated environment representing a more relevant manner in which all human physiology exists.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • Exposome
  • Alcohol Drinking
  • Ethanol
• Keywords:
  • Alcohol
  • Exposome
  • Exposomics
  • Exosomes
  • Extracellular Vesicles
  • Comorbidities
• Source:
  Alcohol (Fayetteville, N.Y.), 2025, v. 122
• DOI:
  https://doi.org/10.1016/j.alcohol.2024.12.003
• ISSN:
  0741-8329 ; 1873-6823
• Pubmed ID:
  39722409
• Pubmed Central ID:
  PMC11918757
• Document Type:
  Text
• Funding:
  I01 BX005886/BX/BLRD VAUnited States/ ; IK6 BX005962/BX/BLRD VAUnited States/ ; P50 AA030407/AA/NIAAA NIH HHSUnited States/ ; U54 OH010162/OH/NIOSH CDC HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  81-89 (20 pdf pages)
• Volume:
  122
• Download URL:
  https://stacks.cdc.gov/view/cdc/261825/cdc_261825_DS1.pdf
• File Type:
  [PDF - 577.92 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:95158195512d6d2679259f76489ff11a02812578bfe71e6d3c87e19f912036a015c9135ed31d0b15cfbb8aad156b5c92757364ace96b67932eb5cb05421cfc30