Tans, Bans, and Sedans: How Distance From Tanning Beds May Save Lives.

Details

• Alternative Title:
  The Journal of Investigative Dermatology, 2025, v. 145, no. 4: Tans, Bans, and Sedans: How Distance From Tanning Beds May Save Lives.
• Journal Article:
  The Journal of Investigative Dermatology
• Personal Author:
  Fisher, David E. ; Geller, Alan C.
• Description:
  Indoor tanning is universally considered to be an important cause of melanoma and keratinocyte carcinomas. Pooling together more than 406,000 individuals from 88 studies, Wehner et al found that more than 450 000 NMSC cases and more than 10 000 melanoma cases each year were attributable to indoor tanning in the United States, Europe, and Australia. 1
  
  Mechanistically, it is well documented that both UVA and UVB wavelengths trigger mutagenic changes in the genomes of skin cells. Moreover, the UV/tanning pathway has been shown to directly stimulate cutaneous synthesis of b-endorphin and to cause addiction-like behavioral changes. UV or sun-seeking risk may therefore be compelled by conscious or even unconscious behavioral influences, which may include ease of access to sources of UV-tanning.2
  
  Two economic models, one from the United States and the second from the UK both concluded that restricting or banning indoor tanning would result in fewer skin cancer cases and deaths. In the United States, restricting indoor tanning among minors younger than 18 years could prevent 61,839 melanoma cases, prevent 6735 melanoma deaths, and save $342.9 million in treatment costs over the lifetime of the 61.2 million youth age 14 years or younger. The projected health and economic benefits increased as indoor tanning were further reduced.3 Compared with the current lack of a consistent policy, a ban on commercial indoor tanning combined with a public information campaign would result in 1206 preventable cases of melanoma, 207 fewer melanoma deaths and 3987 averted cases of keratinocyte cancers over the lifetime of all 18-year-olds (n = 618 873) living in England in 2019. At a cost-effectiveness threshold of £20 000, they determined that there is a 99% likelihood of this policy-based intervention being cost-effective
• Content Notes:
  Author manuscript
• Subjects:
  • Cost-Benefit Analysis
  • Melanoma
  • Models, Economic
  • Health Care Costs
  • Keratinocytes
  • Carcinoma
  • Endorphins
  • Policy
• Source:
  The Journal of Investigative Dermatology, 2025, v. 145, no. 4
• DOI:
  https://doi.org/10.1016/j.jid.2024.05.037
• ISSN:
  0022-202X ; 1523-1747
• Pubmed ID:
  40019458
• Pubmed Central ID:
  PMC12153046
• Document Type:
  Text
• Funding:
  R01 AR072304/AR/NIAMS NIH HHSUnited States/ ; U48 DP006376/DP/NCCDPHP CDC HHSUnited States/ ; P01 CA163222/CA/NCI NIH HHSUnited States/ ; R01 AR043369/AR/NIAMS NIH HHSUnited States/ ; R01 CA249460/CA/NCI NIH HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  721-723 (4 pdf pages)
• Volume:
  145
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/261643/cdc_261643_DS1.pdf
• File Type:
  [PDF - 284.09 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:a1afc7986cce87448f686b58dba4099d24e80f008f02619ad72bcbcc4052e2f9c4101199ad983c95c13395061a4bf7679cad1e377a502d836c15f9a878862a4f