Brief Report: Sexual Partnership Heterogeneity and HIV Seropositivity Among Adolescent Girls and Young Women in Cameroon and Côte D'Ivoire: a Partner-Level Latent Class Analysis.

Details

• Alternative Title:
  Journal of Acquired Immune Deficiency Syndromes (1999), 2025, v. 100, no. 4: Brief Report: Sexual Partnership Heterogeneity and HIV Seropositivity Among Adolescent Girls and Young Women in Cameroon and Côte D'Ivoire: a Partner-Level Latent Class Analysis.
• Journal Article:
  Journal of Acquired Immune Deficiency Syndromes (1999)
• Personal Author:
  Rosen, Joseph G. ; Esso, Yedmel ; Keugoung, Basile ; Lwamba, Chibwe ; Brar, Savvy K. ; Yeh, Ping T. ; Kennedy, Caitlin E. ; Walker, Damilola
• Description:
  Adolescent girls' and young women's (AGYW) heightened HIV vulnerability has been understudied in West and Central Africa, where AGYW account for 1 in 5 new HIV diagnoses. Identifying contextually specific drivers of AGYW's HIV risk can help tailor HIV prevention programming to AGYW in the region.
  
  We pooled data from nationally representative HIV-seroprevalence surveys for sexually active AGYW in Cameroon and Côte d'Ivoire. We used latent class analysis to partition past-year sexual partnerships into discrete typologies based on 6 relationship characteristics: cohabitation, known partner HIV status, condom use at last sex, age mixing (≥5-year age disparity), transactional sex, and likelihood of having sex again. Mixture modeling with cluster-robust standard errors then assessed differences in AGYW's HIV seropositivity by partnership type.
  
  Overall, 5482 AGYW reported 6389 past-year sexual partners. Four distinct partnership types emerged from LCA: Type 1 (Cohabiting, Age-Disparate Partners: ∼46%); Type 2 (Non-Cohabiting, Similar-Aged Partners: ∼15%); Type 3 (One-Off, Age-Disparate Partners: ∼30%); and Type 4 (Non-Cohabiting, Permanent, Age-Disparate Partners: ∼9%). AGYW reporting One-Off, Age-Disparate Partners and Non-Cohabiting, Permanent, Age-Disparate Partners exhibited significantly ( P < 0.05) elevated adjusted odds of HIV seropositivity relative to AGYW reporting Cohabiting, Age-Disparate Partners and Non-Cohabiting, Similar-Aged Partners, respectively.
  
  AGYW reported heterogeneous partnerships that were differentially associated with HIV seropositivity, suggesting discrete relationship characteristics may confer differential HIV acquisition risks among AGYW. Delivery of HIV prevention (ie, long-acting injectable pre-exposure prophylaxis) and diagnostic (ie, HIV self-testing) technologies should be prioritized among AGYW with older, nonpermanent partners, where HIV burdens appear most pronounced.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • Cote d'Ivoire
  • Female
  • Adolescent
  • Sexual Partners
  • Young Adult
  • Sexual Behavior
  • Latent Class Analysis
  • HIV Seropositivity
  • HIV Infections
  More +
• Keywords:
  • adolescents
  • youth
  • HIV prevention
  • population-based study
  • West and Central Africa
• Source:
  Journal of Acquired Immune Deficiency Syndromes (1999), 2025, v. 100, no. 4
• DOI:
  https://doi.org/10.1097/QAI.0000000000003740
• ISSN:
  1525-4135 ; 1944-7884
• Pubmed ID:
  40748485
• Pubmed Central ID:
  PMC12755237
• Document Type:
  Text
• Funding:
  R25MH083620/MH/NIMH NIH HHSUnited States/ ; U2GGH001226/CC/CDC HHSUnited States/ ; P30AI094189/Center for AIDS Research, Johns Hopkins University/ ; U2G GH001226/GH/CGH CDC HHSUnited States/ ; P30 AI094189/AI/NIAID NIH HHSUnited States/ ; R25 MH083620/MH/NIMH NIH HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  Cameroon
• Pages in Document:
  283-288 (11 pdf pages)
• Volume:
  100
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/261211/cdc_261211_DS1.pdf
• File Type:
  [PDF - 649.21 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:bad05ef4e97b796624c3d2284f860e79084f2a02cc931246be58d475525b848518d6827d153433ac744b28e13610ccb702942e042b7466154f3fff157e6e0d99