Cluster Randomized Trial of Text Message Reminders to Retail Staff in Tanzanian Drug Shops Dispensing Artemether-Lumefantrine: Effect on Dispenser Knowledge and Patient Adherence

Bruxvoort, Katia; Festo, Charles; Kalolella, Admirabilis; Cairns, Matthew; Lyaruu, Peter; Kenani, Mitya; Kachur, S. Patrick; Goodman, Catherine; Schellenberg, David

doi:10.4269/ajtmh.14-0126

i

Cluster Randomized Trial of Text Message Reminders to Retail Staff in Tanzanian Drug Shops Dispensing Artemether-Lumefantrine: Effect on Dispenser Knowledge and Patient Adherence

Supporting Files Public Domain

Jul 07 2014
By Bruxvoort, Katia ; Festo, Charles ; Kalolella, Admirabilis ; ...

File Language:

English

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Alternative Title:

Am J Trop Med Hyg
Personal Author:

Bruxvoort, Katia ; Festo, Charles ; Kalolella, Admirabilis ; Cairns, Matthew ; Lyaruu, Peter ; Kenani, Mitya ; Kachur, S. Patrick ; Goodman, Catherine ; Schellenberg, David
Description:

Artemisinin combination therapies are available in private outlets, but patient adherence might be compromised by poor advice from dispensers. In this cluster randomized trial in drug shops in Tanzania, 42 of 82 selected shops were randomized to receive text message reminders about what advice to provide when dispensing artemether-lumefantrine (AL). Eligible patients purchasing AL at shops in both arms were followed up at home and questioned about each dose taken. Dispensers were interviewed regarding knowledge of AL dispensing practices and receipt of the malaria-related text messages. We interviewed 904 patients and 110 dispensers from 77 shops. Although there was some improvement in dispenser knowledge, there was no difference between arms in adherence measured as completion of all doses (intervention 68.3%, control 69.8%, p [adjusted] = 0.6), or as completion of each dose at the correct time (intervention 33.1%, control 32.6%, p [adjusted] = 0.9). Further studies on the potential of text messages to improve adherence are needed.
Subjects:

Antimalarials Artemether Artemisinins Articles Child Child, Preschool Commerce Drug Therapy, Combination Ethanolamines Female Fluorenes Follow-Up Studies Humans Infant Lumefantrine Malaria Male Patient Compliance Plasmodium Text Messaging
Source:

Am J Trop Med Hyg. 2014; 91(4):844-853.
Document Type:

Journal Article
Place as Subject:

Tanzania
Volume:

91
Issue:

4
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:17b9bea206746e57f81a95d76e2700e1c9e4e6c7596066bb0bf7ec23faef8c5f
Download URL:

https://stacks.cdc.gov/view/cdc/26086/cdc_26086_DS1.pdf
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[PDF - 901.22 KB ]

File Language:

English

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