Details:

Alternative Title:
eLife
Personal Author:
Russell, Colin A ; Kasson, Peter M ; Donis, Ruben O ; Riley, Steven ; Dunbar, John ; ... More +
Russell, Colin A ; Kasson, Peter M ; Donis, Ruben O ; Riley, Steven ; Dunbar, John ; Rambaut, Andrew ; Asher, Jason ; Burke, Stephen ; Davis, C Todd ; Garten, Rebecca J ; Gnanakaran, Sandrasegaram ; Hay, Simon I ; Herfst, Sander ; Lewis, Nicola S ; Lloyd-Smith, James O ; Macken, Catherine A ; Maurer-Stroh, Sebastian ; Neuhaus, Elizabeth ; Parrish, Colin R ; Pepin, Kim M ; Shepard, Samuel S ; Smith, David L ; Suarez, David L ; Trock, Susan C ; Widdowson, Marc-Alain ; George, Dylan B ; Lipsitch, Marc ; Bloom, Jesse D Less -
Description:
Assessing the pandemic risk posed by specific non-human influenza A viruses is an important goal in public health research. As influenza virus genome sequencing becomes cheaper, faster, and more readily available, the ability to predict pandemic potential from sequence data could transform pandemic influenza risk assessment capabilities. However, the complexities of the relationships between virus genotype and phenotype make such predictions extremely difficult. The integration of experimental work, computational tool development, and analysis of evolutionary pathways, together with refinements to influenza surveillance, has the potential to transform our ability to assess the risks posed to humans by non-human influenza viruses and lead to improved pandemic preparedness and response.
Subjects:
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Base Sequence Biological Evolution Emergence Epidemiological Monitoring Feature Article Genomics And Evolutionary Biology Geography Human Humans Influenza Influenza, Human Influenza A Virus Microbiology And Infectious Disease Models, Biological Pandemic Pandemics Public Health Risk Assessment Science Forum Viruses
Source:
eLife. 3
Pubmed ID:
25321142
Pubmed Central ID:
PMC4199076
Document Type:
Journal Article
Funding:
U01 GM110721/GM/NIGMS NIH HHS/United States ; 095066/Wellcome Trust/United Kingdom ; R01 GM098304/GM/NIGMS NIH HHS/United States ; MR/J008761/1/Medical Research Council/United Kingdom ; MR/K010174/1/Medical Research Council/United Kingdom ; ... More +
U01 GM110721/GM/NIGMS NIH HHS/United States ; 095066/Wellcome Trust/United Kingdom ; R01 GM098304/GM/NIGMS NIH HHS/United States ; MR/J008761/1/Medical Research Council/United Kingdom ; MR/K010174/1/Medical Research Council/United Kingdom ; 095831/Wellcome Trust/United Kingdom ; R01 GM102198/GM/NIGMS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f7d5bff66cbbe3555b99b8375200d51df3d9c99d97733fd2ad7727ca96b45330
Download URL:
https://stacks.cdc.gov/view/cdc/26075/cdc_26075_DS1.pdf
File Type:

Supporting Files

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