New carbapenem-resistant Enterobacteriaceae warrant additional action by healthcare providers
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New carbapenem-resistant Enterobacteriaceae warrant additional action by healthcare providers

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    February 14, 2013, 12:30 ET


    Carbapenem-resistant Enterobacteriaceae (CRE) are untreatable or difficult-to-treat multidrug resistant organisms that are emerging in the United States. Because of increased reports of these multidrug-resistant organisms, CDC is alerting clinicians about the need for additional prevention steps regarding CRE. Key points include:

    • While still uncommon, reports of unusual forms of CRE (e.g., New Delhi Metallo-Plactamase and Verona Integron-mediated Metallo-P-lactamase) in the United States are increasing. Of the 37 unusual forms of CRE that have been reported in the United States, the last 15 have been reported since July, 2012.

    • This increase highlights the need for U.S. healthcare providers to act aggressively to prevent the emergence and spread of these unusual CRE organisms.

    • Current CDC guidance includes key elements of CRE prevention (e.g., use of Contact Precautions) in healthcare settings.

    • Because the vast majority of these unusual organisms were isolated from patients who received overnight medical treatment outside of the United States, additional measures described in this HAN advisory are now recommended to be taken when such patients are hospitalized in the United States.

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