Use of ciprofloxacin or doxycycline for postexposure prophylaxis for prevention of inhalational anthrax
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields



Publication Date Range:


Document Data


Document Type:






Clear All

Query Builder

Query box

Clear All

For additional assistance using the Custom Query please check out our Help Page


Use of ciprofloxacin or doxycycline for postexposure prophylaxis for prevention of inhalational anthrax

Filetype[PDF-1.12 MB]

  • English

  • Details:

    • Journal Article:
    • Description:
      Wednesday, October 31, 2001, 13:45 EST (1:45 PM EST)


      Interim recommendations, MMWR 50(no 41):893 Oct 19,2001, for postexposure prophylaxis to prevent inhalational anthrax after exposure to B. anthracis spores recommend ciprofloxacin or doxycycline as initial therapy in situations associated with the current bioterrorist attack in the United States.

      EFFECTIVENESS: There is no evidence which demonstrates that ciprofloxacin is more or less effective than doxycycline for postexposure prophylaxis for prevention of infection with B. anthracis

      RESISTANCE: Widespread use of any antibiotic will promote resistance. Many common pathogens are already resistant to tetracyclines such as doxycycline. However, ciprofloxacin resistance is not yet common in these same organisms. To preserve the effectiveness of ciprofloxacin against other infections, use of doxycycline for prevention of B. anthracis infection is reasonable. Ciprofloxacin is an effective antimicrobial for a variety of other bacterial infections. Thus, the wide use of this drug in thousands of individuals may lead to increased resistance of other bacterial pathogens to ciprofloxacin and other fluroquinolones, and limit the usefulness of these agents.

      SIDE EFFECTS: On the basis of side-effect profiles (see below), the history of reactions, or the clinical setting, either doxycycline or ciprofloxacin may be preferable for an individual patient.

      Event Type: anthrax terrorism event

      Context: countermeasures/therapeutics

      Event Type: Man-made

      Agent Type: bacteria

      Specify Agent (Name): anthrax

      International: no

      Intentional/Unintentional: intentional

    • Series:
    • Document Type:
    • Place as Subject:
    • Location:
    • Main Document Checksum:
    • File Type:

    Supporting Files

    • No Additional Files

    More +

    You May Also Like

    Checkout today's featured content at