Chronic respiratory disease in adult outpatients in three African countries: a cross-sectional study.

Details

• Personal Author:
  Balmes J ; Binegdie AB ; Burney PJ ; Devereux G ; El Sony A ; Haile T ; Lesosky M ; Meme H ; Miheso B ; Mortimer K ; Osman R ; Zurba L
• Description:
  BACKGROUND: The greatest burden of chronic respiratory disease is in low- and middle-income countries, with recent population-based studies reporting substantial levels of obstructive and restrictive lung function. OBJECTIVE: To characterise the common chronic respiratory diseases encountered in hospital outpatient clinics in three African countries. METHODS: This was a cross-sectional study of consecutive adult patients with chronic respiratory symptoms (>8 weeks) attending hospital outpatient departments in Ethiopia, Kenya and Sudan. Patients were assessed using a respiratory questionnaire, spirometry and chest radiography. The diagnoses of the reviewing clinicians were ascertained. RESULT: A total of 519 patients (209 Kenya, 170 Ethiopia, 140 Sudan) participated; the mean age was 45.2 years (SD 16.2); 53% were women, 83% had never smoked. Reviewing clinicians considered that 36% (95% CI 32-40) of patients had asthma, 25% (95% CI 21-29) had chronic bronchitis, 8% (95% CI 6-11) chronic obstructive pulmonary disease (COPD), 5% (95% CI 4-8) bronchiectasis and 4% (95% CI 3-6) post-TB lung disease. Spirometry consistent with COPD was present in 35% (95% CI 30-39). Restriction was evident in 38% (95% CI 33-43). There was evidence of sub-optimal diagnosis of asthma and COPD. CONCLUSION: In Ethiopia, Kenya and Sudan, asthma, COPD and chronic bronchitis account for the majority of diagnoses in non-TB patients with chronic respiratory symptoms. The suboptimal diagnosis of these conditions will require the widespread use of spirometry. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Chronic Disease Occupational Health Radiography Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety Tuberculosis
• Keywords:
  Asthma; Chronic Diseases; Chronic Obstructive Pulmonary Disease; COPD; Bronchitis; Tuberculosis; TB; Respiratory Diseases; Cross Sectional Studies; Spirometry; Chest Radiography; Author Keywords: Chronic Respiratory Symptoms; Spirometry; COPD; Asthma; Africa; Ethiopia; Kenya; Sudan; Hospital Clinics
• ISSN:
  1027-3719
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  18-25
• Volume:
  26
• Issue:
  1
• NIOSHTIC Number:
  nn:20064844
• Citation:
  Int J Tuberc Lung Dis 2022 Jan; 26(1):18-25
• Contact Point Address:
  Amsalu Bekele Binegdie, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
• Email:
  kjm20@cam.ac.uk
• Federal Fiscal Year:
  2022
• Performing Organization:
  University of California, Berkeley
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  The International Journal of Tuberculosis and Lung Disease
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:df69711360192a06a11e45a86daba22352db0229f6d12649e7ec37802d70bd2376ef2ab9a594b39f1d5753dac3cf6dd9491f537e55d3623fa83bf25f90e81317
• Download URL:
  https://stacks.cdc.gov/view/cdc/248759/cdc_248759_DS1.pdf
• File Type:
  [PDF - 98.50 KB ]